Product Name: Zinc Pyrithione
Chemical Formula: C10H8N2O2S2Zn
Synonyms: 1-Hydroxy-2-pyridinethione zinc salt, ZPT
Recommended Uses: Antimicrobial agent in personal care products (shampoo, soap), antifungal treatments, paint and polymer biocide
Manufacturer Contact: [Contact details specific to manufacturer]
CAS Number: 13463-41-7
Emergency Phone: [Company emergency contact/Poison Control]
Appearance: White/off-white crystalline powder
Relevant Identified Uses: Dandruff control, mildew inhibitor, preservative in cosmetics and building materials
Hazard Classifications: Acute toxicity (oral, dermal, inhalation), skin and eye irritant, aquatic toxicity
Signal Word: Warning
Hazard Statements: Harmful if swallowed. Causes eye irritation. Toxic to aquatic life with long-lasting effects.
Pictograms: Exclamation mark, Environment
Precautionary Statements: Avoid inhalation and ingestion. Keep out of reach of children. Avoid release to the environment.
Potential Health Effects: Short-term exposure may cause skin, eye, and respiratory irritation; systemic effects possible if ingested
Chronic Effects: Long-term or repeated exposure may affect liver and kidney function
Chemical: Zinc Pyrithione
Concentration: >97% by weight
CAS Number: 13463-41-7
EINECS Number: 236-671-3
Impurities: Minor impurities below 1% (identity varies by manufacturer)
Other Components: No other significant components or stabilizers present
Inhalation: Move person to fresh air. Seek medical attention if symptoms persist. Provide oxygen if breathing is difficult.
Skin Contact: Remove contaminated clothing and rinse skin with plenty of water. Wash with soap for thorough decontamination.
Eye Contact: Hold eyelids open and rinse with running water for at least 15 minutes. Get medical help if irritation develops.
Ingestion: Do not induce vomiting. Rinse mouth with water. Seek immediate medical advice.
Most Important Symptoms: Irritation, nausea, headache, possible allergic reactions
Note to Physician: Treat symptomatically and provide supportive care
Suitable Extinguishing Media: Foam, dry powder, carbon dioxide, water spray (fine mist)
Unsuitable Media: Direct water jets (may spread chemical)
Hazards From Combustion: Produces irritating or toxic fumes including zinc oxides, sulfur oxides, nitrogen oxides during combustion
Protective Equipment: Self-contained breathing apparatus and full protective clothing
Special Precautions: Move containers from fire area if safe. Avoid run-off contamination to water sources.
Personal Precautions: Avoid contact with skin, eyes, and clothing. Wear suitable protective equipment—gloves, goggles, dust mask.
Environmental Precautions: Prevent product entry into drains, sewers, or waterways. Avoid soil contamination.
Spill Clean-Up Methods: Scoop up solid material, collect in labeled containers for disposal. Wash area with water and detergent. Ventilate area.
Decontamination: Use absorbent materials for residues. Dispose of protective equipment safely after clean-up.
Precautions for Safe Handling: Minimize dust generation. Avoid breathing dust and prevent skin or eye contact. Ensure good ventilation in handling area.
Hygiene Measures: Do not eat, drink, or smoke in work area. Wash hands and affected skin thoroughly after handling.
Storage Conditions: Store in cool, dry, well-ventilated area, away from incompatible materials (acids, oxidizers).
Container Requirements: Keep containers tightly closed and properly labeled. Use corrosion-resistant materials.
Exposure Limits: No established OSHA PEL or ACGIH TLV; follow workplace hygiene regulations.
Technical Controls: Provide local exhaust ventilation or general ventilation as needed.
Personal Protective Equipment: Protective gloves (nitrile or rubber), safety goggles, lab coat or apron. Use dust mask or respirator if airborne concentrations increase.
Environmental Controls: Prevent product discharge to environment, monitor air and water as appropriate.
Additional Measures: Wash contaminated clothing before reuse.
Appearance: White or off-white crystalline powder
Odor: Slight characteristic odor
pH: 7-9 as 1% aqueous suspension
Melting Point: >240°C (decomposes)
Boiling Point: Not applicable (decomposes)
Flash Point: Not determined (inorganic solid)
Solubility: Slightly soluble in water (~8 mg/L at 20°C), more soluble in organic solvents
Specific Gravity: ~1.6 (water = 1)
Vapor Pressure: Negligible at ambient temperature
Partition Coefficient: log Kow ~1.7
Stability: Stable at room temperature if stored dry and away from light
Reactivity: No dangerous reactions expected under recommended conditions
Chemical Stability: Stable in closed containers under normal storage and handling
Conditions to Avoid: Excessive heat, direct sunlight, strong acids and oxidizing agents
Incompatible Materials: Strong oxidizers, acids, bases
Hazardous Decomposition: May form toxic gases including sulfur oxides, nitrogen oxides, and zinc oxides under fire or extreme heat
Polymerization: Product will not undergo hazardous polymerization
Acute Toxicity: Oral LD50 (rat): 269 mg/kg; Dermal LD50 (rabbit): >2000 mg/kg
Inhalation: Dust may cause respiratory irritation and coughing
Skin Contact: May cause irritation, redness, or rash. Prolonged or repeated contact can trigger allergic reactions
Eye Contact: Contact causes irritation and redness
Chronic Exposure: Animal studies show liver and kidney changes at high repeated doses
Carcinogenicity: Not listed as carcinogen by NTP, IARC, or OSHA
Mutagenicity: Negative in in-vitro genetic toxicity tests
Reproductive Toxicity: No evidence in animal experiments under typical exposure levels
Ecotoxicity: Highly toxic to fish and aquatic invertebrates. LC50 (96hr, rainbow trout): ~0.16 mg/L
Persistence and Degradability: Not readily biodegradable; low persistence due to photodegradation in water
Bioaccumulation Potential: Moderate bioaccumulation based on octanol-water partition coefficient
Mobility in Soil: Low mobility; binds to sediments
Environmental Precautions: Avoid contamination of surface waters. Even small quantities can disrupt aquatic life.
Other Adverse Effects: Can disrupt microbial communities in wastewater if discharged in bulk
Waste Methods: Treat as hazardous waste. Dispose of in accordance with local, regional, national, and international regulations
Container Disposal: Triple-rinse, puncture, and dispose of empty containers through licensed facility
Prevent Release: Do not pour into drains, sewers, or natural water bodies
Preferred Treatment: Incineration at approved facility; landfilling as last resort with safeguards against leaching
UN Number: 3077
UN Proper Shipping Name: Environmentally Hazardous Substance, Solid, N.O.S. (contains Zinc Pyrithione)
Transport Hazard Class: 9
Packing Group: III
Labels Required: Environmentally hazardous substances
Marine Pollutant: Yes
Transport Regulations: Subject to IMDG, IATA, ADR rules. Follow specific national restrictions for movement of hazardous substances.
Regulatory Status: Registered under EPA for specific biocidal applications; usage permitted in limited concentrations in cosmetics per EU, US, and Asia-Pacific guidelines
US Regulations: TSCA listed. Controlled under FIFRA (pesticidal and antimicrobial claims)
EU Regulations: Approved as preservative in rinse-off cosmetics at concentrations up to 1% active ingredient; tighter restrictions for leave-on skin products
Other Countries: Limits vary between jurisdictions; consult local authorities
Workplace Exposure: Employer must implement chemical hazard communication and personal protective measures where product handled above threshold levels
Labeling Requirements: Product must carry warning pictograms, hazard statements, precautionary language reflecting aquatic toxicity and acute health risks
