Tetramethylammonium bromide forms the backbone of many chemical processes today. Known under its molecular formula C4H12BrN, each unit combines a tetramethylammonium cation and a bromide anion. Chemists working in laboratories and in larger production settings often pick it for its role as a quaternary ammonium compound. Its CAS Number is 64-20-0, recognized for high purity and distinct molecular properties. The substance stands out because of versatility. One solid can exist as flakes, powder, crystalline pearls, or as a concentrated solution depending on product requirements. You spot this compound everywhere from basic scientific research to fine industrial synthesis.
The structure stays simple: four methyl groups connect to a single nitrogen atom, forming a compact, symmetrical geometry. This molecular form grants significant stability and solubility, setting the stage for reliable chemical performance. With a density near 1.398 g/cm3, the solid keeps its white, sometimes translucent appearance across most physical formats. As a crystal, it reflects light cleanly and remains dry to the touch, never sticky even when poured as powder or flakes. Once dissolved in water, it creates a clear solution. Melting point hovers around 228 to 242°C, which means it stays solid under normal environmental conditions. So, researchers don’t worry about it breaking down at room temperature or losing integrity on storage shelves.
This compound maintains strict standards in chemical supply chains. Pureness often measures at 99% minimum, limiting risks from unwanted contaminants. Analysts frequently check moisture content, with manufacturers holding it below 0.5% to avoid unwanted clumping or breakdown during use. Standard specification lists include description of appearance, molecular weight, melting point, density, solubility in water and ethanol, and detailed purity confirmation. Buyers rely on the HS Code 29239000 for import or export labeling. Whether transported as raw material, processed for a final product, or measured for research-grade standards, the substance typically abides by these identifiers for traceability.
Across the supply chain, tetramethylammonium bromide adapts. Chemists might prefer solid flakes, which pour well and offer a manageable, stackable product. Powder remains popular when dissolution needs speeding up — in my own lab, nothing mixes faster for buffer preparation. Crystalline pearls, smooth and nearly spherical, reduce the risk of dusting and airborne exposure during weighing or transfer. Liquid forms and pre-mixed solutions simplify work on the bench. These ready-to-use forms mean faster workflows and less direct handling, important when time and cleanliness are at a premium.
This chemical plays a role in organic synthesis, phase transfer catalysis, ion exchange, and even as a component in specialty electrolytes. In industrial settings, the ability to rely on predictable purity and density can spell the difference between efficient, safe production and delays or hazards. In research, accurate molecular properties matter. Miss a decimal in formula mass, and experiment results skew. Whether acting as a template for zeolite formation or facilitating anion exchange, material form almost always tracks back to source purity and reliable construction of the tetramethylammonium structure.
Every chemical carries responsibilities. Tetramethylammonium bromide deserves respect for its specific hazards. Solid or dissolved, it poses health risks if inhaled, ingested, or absorbed through the skin. Touch or inhalation might trigger irritation, allergic reactions, or more acute toxicological responses if not handled with gloves or fume extraction. Both industrial and lab users consult its safety data pages before working. I always check recommended ventilation rates and ensure all waste funnels directly to secure containers, staying mindful of environmental rules. It sits in the lower hazard class compared to stronger ammonium derivatives, but still counts as harmful, especially in concentrated environments or high-volume handling.
Best practices hinge on focused training, clear labeling, and accessible storage. In my own facility, every chemical cupboard holding tetramethylammonium bromide posts signs detailing its molecular formula, density, melting point, and HS Code. Team members know to reference each batch’s certificate of analysis and pay close attention to its listed purity. Proper PPE makes a real impact: gloves, goggles, long sleeves, and a well-ventilated workspace all stand between routine operation and a potential incident. Waste management policies follow local regulations — we store spent material and washings separately for specialist disposal. Only through respect and consistency does the chemical earn its place as an asset and not a liability.
Many chemical manufacturers look for safer replacements. A few explore green chemistry approaches, designing systems using less hazardous or biodegradable substitutes. Professional bodies increasingly stress transparency in sourcing, so users know exactly where and how a batch of raw materials originates. Digital tracking and rigorous supplier vetting form part of a modern solution — they lessen the chance of tainted shipments and support end-to-end responsibility. As someone who has navigated procurement, supplier choice goes beyond price; reliable delivery, full documentation, and honest communication mark a trustworthy source.
Tetramethylammonium bromide delivers value through clarity of structure, purity, and functionality across solid, flaked, and liquid states. Teams leveraging its material strengths in research or industry see measurable benefits, provided they respect its chemical risk and track each measure for sustained safety. Every shipment, label, and safety step supports a broader future in which industry and science trust the materials shaping our world.
