Iso Propyl Bromide stands out as a clear, colorless liquid with a strong odor that signals you are handling something potent. In the world of raw materials for chemical syntheses, this compound—recognized under the molecular formula C3H7Br—serves both as a building block and a reagent. Its full name, 2-Bromopropane, points to the arrangement of atoms in the molecule, where one bromine atom links to the second carbon in a three-carbon propane chain. With a molar mass of about 122.99 g/mol, the structure plays a role in determining reactivity and physical properties. This compound appears as a liquid at room temperature and can move between phases with cooling or gentle heating.
The chemical’s density measures around 1.31 g/cm³ at 20°C, showing the impact of having a heavy bromine atom in a relatively small molecule. It boils at about 59°C and freezes near -89°C. These numbers matter, especially in industrial setups, where temperature control determines how safe and effective a process will run. IPB comes in drums or standard chemical containers and usually doesn’t have forms like flakes, powder, or pearls. Sometimes suppliers can provide a solution in specific solvents, but the pure material stays liquid at room temperature. Water solubility sits low, although the compound mixes well with organic solvents like alcohols, acetone, or ether. It doesn’t show up as a crystal at standard conditions, and long storage in sunlight or heat leads to decomposition, with the risk of toxic vapors. Meeting the HS Code 2903.30.00, regulations cover import, export, and workplace use for safety and compliance.
Industries who work with IPB use it to introduce the isopropyl group to other organic compounds, especially in pharmaceutical and agrochemical syntheses. It can be found as an intermediate in the preparation of drugs, specialty chemicals, and even in some flame retardants. The chemical’s electrophilic nature makes reactions with nucleophiles precise and efficient, which is the secret behind its popularity in labs and factories. For companies focused on chemical R&D, sourcing quality IPB comes down to purity, stable packaging, and clear supply chain documentation. Most batches aim for high purity, free from water, acid, or unreacted starting materials, because impurities shift yields or introduce unwanted side products.
Iso Propyl Bromide doesn’t rank among the most dangerous chemicals in everyday language, but that can mislead. The liquid catches fire at higher temperatures and generates toxic fumes including hydrogen bromide and phosgene if burned. Vapors can overwhelm the senses quickly, so ventilation stays crucial for anyone dispensing or reacting the chemical in volume. Prolonged skin contact can cause irritation, redness, or burns, and inhalation irritates the respiratory tract. The Safety Data Sheet clearly lists the need for goggles, gloves, and, if working in large quantities, a face shield or respirator. Spilled IPB evaporates, but brominated organic compounds can linger in soil and water, where they might harm aquatic life or break down only slowly. Disposal routines always follow hazardous waste protocols, with neutralization and specialist treatment to break down the compound safely.
Anyone using or considering IPB for manufacturing must weigh both benefits and risks. From my time working in a research lab, replacing halogenated intermediates in some syntheses meant running through cost, yield, and environmental impact. Some reactions still demand IPB for its unique performance, but greener chemistry keeps challenging us to find new routes with lower toxicity or improved biodegradability. Engineers and chemists continue to develop alternative reagents, and regulatory bodies push companies to limit emissions. Reducing storage volumes, keeping containers secure, and training workers in emergency response all help minimize incidents. Communities living near chemical processing sites expect companies to stick to best practices, manage air filtration, and limit runoff. Embracing transparent reporting goes beyond compliance—it’s a mark of respect for everyone downstream from a decision to use or handle IPB.
