Product Name: Sodium Pyrithione
Chemical Name: Sodium Omadine
Synonyms: SPT, 2-Pyridinethiol-1-oxide sodium salt
CAS Number: 3811-73-2
Molecular Formula: C5H4NNaOS
Molecular Weight: 149.15 g/mol
Recommended Use: Antimicrobial agent in paints, personal care, metalworking fluids
Manufacturer/Supplier: Contact supplier directly for details
Emergency Contact: Refer to local country emergency services and supplier’s emergency line
GHS Classification: Acute Toxicity Oral (Category 4), Skin Sensitizer (Category 1), Eye Damage (Category 1), Aquatic Acute Hazard (Category 1), Aquatic Chronic Hazard (Category 1)
Signal Word: Danger
Hazard Statements: Causes serious eye damage. Harmful if swallowed. May cause an allergic skin reaction. Very toxic to aquatic life with long lasting effects.
Pictograms: Corrosion, Exclamation Mark, Environment
Precautionary Statements: Avoid release to the environment. Wear protective gloves and eye protection. IF SWALLOWED: Call a poison center if you feel unwell. IF IN EYES: Rinse for several minutes and remove contact lenses if present. Wash thoroughly after handling.
Chemical: Sodium pyrithione
Concentration (%): ≥ 95%
Impurities: May include low levels of other pyrithione derivatives
EC Number: 223-296-5
Other Components: Typically negligible; batch analysis should confirm trace impurity levels as per supplier certificate of analysis
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses, continue rinsing. Seek immediate medical attention.
Skin Contact: Remove contaminated clothing. Wash exposed skin with soap and water. Watch for signs of rash or irritation.
Inhalation: Move person to fresh air. If breathing difficulty persists, seek medical advice.
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention, and provide the container or label as reference.
Notes for Physicians: Treat symptomatically and supportively. Monitor for allergic reactions or respiratory distress.
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Media: Direct water jet may spread material
Specific Hazards: Product decomposes and may release toxic fumes, including sulfur oxides and nitrogen oxides
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear
Special Instructions: Contain runoff to prevent entry into drains or water bodies. Cool containers exposed to fire.
Personal Precautions: Use personal protective equipment including gloves, goggles, and respiratory protection in case of dust
Environmental Precautions: Prevent spillage from entering drains, surface water, or soil
Containment: Sweep spilled material carefully. Use absorbents for liquid spills. Avoid dust formation.
Cleanup Methods: Collect in closed, labeled containers for disposal. Clean contaminated surfaces with plenty of water.
Disposal: Dispose as hazardous chemical waste in compliance with local regulations.
Handling: Handle in well-ventilated areas. Minimize generation of dust. Avoid contact with skin, eyes, and clothing.
Storage Conditions: Store in tightly closed containers in a cool, dry, well-ventilated place. Keep away from food, drink, and incompatible substances such as strong oxidizing agents.
Incompatibilities: Strong acids, oxidizers, reducing agents
Special Precautions: Ensure proper labeling and secure containment.
Occupational Exposure Limits: No established national limits. Use local exhaust ventilation to control airborne levels.
Engineering Controls: Mechanical ventilation, eye-wash stations, emergency showers
Personal Protection: Chemical-resistant gloves, safety goggles, laboratory coat, and dust mask or respirator where exposure risk exists
Environmental Controls: Prevent unintended release to water courses and soil by using containment systems
Physical Form: White to light yellow crystalline powder
Odor: Slight odor
pH (1% solution): Approximately 9.5
Melting Point: 300°C (decomp.)
Boiling Point: Not applicable due to decomposition
Solubility: Soluble in water
Density: About 1.45 g/cm³
Vapor Pressure: Negligible
Partition Coefficient: Log Kow ≈ -0.77
Other Information: Stable under recommended storage and handling conditions
Chemical Stability: Stable under normal storage and handling at room temperature
Hazardous Reactions: Contact with strong acids or oxidizers leads to decomposition and hazardous gases production
Conditions to Avoid: Avoid heating above decomposition temperature, high humidity, and direct sunlight
Materials to Avoid: Strong acids, oxidizers, reducing agents
Decomposition Products: Releases sulfur dioxide, nitrogen oxides, and sodium oxide
Routes of Exposure: Inhalation, ingestion, skin, eye
Acute Toxicity: Oral LD50 (rat): 839 mg/kg
Inhalation Toxicity: LC50 data not available; avoid inhaling dusts
Skin Irritation: May cause irritation or allergic skin reaction
Eye Irritation: Causes serious eye damage
Chronic Effects: Long-term skin contact can cause sensitization
Carcinogenicity: Not classified as carcinogen by IARC, NTP, or OSHA
Other Effects: Repeated exposure may cause dermatitis
Ecotoxicity: Very toxic to aquatic organisms. EC50 (Daphnia magna, 48 hr): 0.22 mg/L
Bacterial Inhibition: May inhibit microbial activity in soil or water
Persistence and Degradability: Limited information available; chemical may persist in aquatic environments
Bioaccumulation: Low potential (Log Kow -0.77)
Mobility: Highly mobile in water
Other Adverse Effects: Prevent release into environment, even small spills can harm aquatic life
Disposal Methods: Store waste in a designated, labeled container. Do not dispose of with household or municipal waste.
Waste Regulation: Dispose in accordance with local, regional, and national regulations for hazardous waste.
Packing for Disposal: Use suitable, sealed containers. Avoid contamination of disposal workers.
Contaminated Packaging: Decontaminate or dispose as hazardous waste.
Recycling: Product is typically not recycled; contact professional disposal service
UN Number: Consult specific transport regulation for final assignment; often not regulated under standard modes
ADR/RID Class: Consult local transport rules
IMDG Code: Environmentally hazardous substance
ICAO/IATA: Consult airline and country regulations; chemical may require Environmentally Hazardous Substance label
Packing Group: III (when classified as toxic or dangerous)
Marine Pollutant: Yes
Precautions During Transport: Secure containers to prevent tipping, avoid breakage, protect from moisture and heat
Inventory Status: Listed on US TSCA, EU REACH, Australia AICS, and other major chemical inventories
Labeling Requirements: GHS and local chemical regulation-compliant labeling
Other National Regulations: SPT regulated under biocidal products directives in the EU, and certain occupational safety regulations in North America
SARA 313 (US): Not listed
California Proposition 65: Not listed
Key Restrictions: Vary by application and country; always consult national law for permitted uses and restrictions
Use in Food/Pharma: Strictly prohibited
Worker Protection: Required under OSHA or equivalent legislation, including right-to-know and hazard communication standards
