Product Name: N-Propyl Bromide
Synonyms: 1-Bromopropane, nPB
Chemical Formula: C3H7Br
CAS Number: 106-94-5
Recommended Use: Solvent for cleaning, degreasing, adhesive sprays
Manufacturer Information: Contact information required for supplier or distributor
Emergency Contact: Poison control center or local emergency number relevant to user’s location
GHS Classification: Flammable liquid, Acute toxicity by inhalation, Skin and eye irritant, Reproductive toxicity, Specific target organ toxicity
Signal Word: Danger
Hazard Statements: Causes serious eye and skin irritation, Harmful if swallowed, Flammable liquid and vapor, May damage fertility or unborn child, Central nervous system depression
Pictograms: Flame, exclamation mark, health hazard, skull and crossbones
Precautionary Statements: Keep away from heat, Use in well-ventilated area, Wear protective clothing, Do not breathe vapors, Wash hands after use
Chemical Name: N-Propyl Bromide
Concentration: ≥ 99%
Impurities: Possible trace quantities of 2-bromopropane, water, proprietary stabilizers
Other Information: Product does not contain additives beyond those required for shelf stability
Inhalation: Remove person to fresh air, keep at rest, seek medical advice if symptoms continue, administer oxygen if breathing is difficult
Skin Contact: Remove contaminated clothing, wash affected area with soap and water for at least 15 minutes, do not use solvents to clean skin
Eye Contact: Rinse thoroughly with water for several minutes, remove contact lenses, get medical attention immediately
Ingestion: Rinse mouth with water, do not induce vomiting, seek medical attention
Most Important Symptoms: Headache, nausea, dizziness, confusion, skin redness or blistering, respiratory irritation
Notes to Physician: Supportive care and symptomatic treatment, monitor for potential central nervous system depression, risk of delayed pulmonary edema
Suitable Extinguishing Media: Carbon dioxide, dry chemical, foam, water spray (do not use direct water jet)
Special Hazards: Vapors can form explosive mixtures with air, combustion produces toxic and corrosive fumes (hydrogen bromide, carbon oxides)
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Specific Methods: Use water spray to cool containers, prevent run-off from entering water sources or sewers, evacuate area if fire involves large quantities
Personal Precautions: Evacuate area, ensure adequate ventilation, eliminate ignition sources, use explosion-proof equipment and non-sparking tools
Environmental Precautions: Prevent spillage from entering drains, water bodies, soil; notify authorities if significant environmental impact suspected
Methods for Cleaning Up: Absorb spill with inert material, transfer to sealed labeled container for disposal, ventilate area after cleanup, decontaminate surfaces with detergent and water, dispose of contaminated materials safely
Handling: Use only in well-ventilated areas, ground containers and equipment, avoid breathing vapors and contact with skin or eyes, keep away from heat, sparks, open flames
Storage: Store in a tightly closed container, keep in a cool, dry, ventilated location away from sunlight, incompatible materials include acids, bases, oxidizers, aluminum
Special Requirements: Segregate from food and beverages, use secondary containment if possible, implement static discharge controls, provide emergency eyewash and safety shower in work area
Occupational Exposure Limits: ACGIH TLV (2018) 0.1 ppm TWA, OSHA PEL not established at the federal level
Engineering Controls: Use local exhaust ventilation, explosion-proof ventilation systems, continuous air monitoring recommended for confined spaces
Personal Protective Equipment (PPE): Butyl rubber or other chemical-resistant gloves, chemical splash goggles, impervious protective clothing, NIOSH-approved respiratory protection (organic vapor cartridge or supplied-air) where exposure limits might be exceeded
Hygiene Measures: Remove contaminated clothing and wash thoroughly after handling, prohibit eating, drinking, and smoking in work areas, maintain eyewash stations and showers nearby
Appearance: Colorless liquid
Odor: Sweet, ether-like
Odor Threshold: 135 ppm
pH: Not applicable
Melting Point/Freezing Point: -110°C
Boiling Point: 71°C
Flash Point: 23°C (closed cup)
Evaporation Rate: Rapid
Flammability: Flammable
Vapor Pressure: 140 mmHg at 20°C
Vapor Density: 4.3 (air = 1)
Relative Density: 1.35 g/cm³ at 20°C
Solubility in Water: Slight (2.5 g/L at 25°C)
Partition Coefficient (log Kow): 2.1
Auto-Ignition Temperature: 407°C
Decomposition Temperature: 300°C (approx.)
Viscosity: Not determined
Chemical Stability: Stable under normal conditions, may decompose when exposed to heat, light, moisture
Conditions to Avoid: Heat, sparks, open flames, incompatible chemicals, direct sunlight
Incompatible Materials: Strong acids, strong bases, oxidizers, powdered metals, active metals (aluminum, potassium)
Hazardous Decomposition Products: Hydrogen bromide, bromine gas, carbon oxides, phosgene in a fire scenario
Hazardous Reactions: Exothermic reactions with reactive metals possible, polymerization does not occur without catalyst
Likely Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Effects: Central nervous system depression, dizziness, nausea, confusion, headache, drowsiness, skin and eye irritation
Chronic Effects: Peripheral neuropathy, reproductive toxicity, possible carcinogenicity based on animal studies
Toxicity Data: LD50 oral (rat): ~3,260 mg/kg; LC50 inhalation (rat, 4h): 25,300 mg/m³
Sensitization: Not expected based on available data
Mutagenicity/Carcinogenicity: Evidence of mutagenicity in vitro, animal studies suggest potential carcinogenic risk, IARC classifies 1-bromopropane as possibly carcinogenic to humans (Group 2B)
Reproductive Toxicity: Linked to decreased fertility and developmental toxicity in animal studies
Symptoms of Overexposure: Numbness, tingling, difficulty walking, memory loss, sleep disturbance
Medical Conditions Aggravated: Existing neurological, respiratory, or skin conditions
Ecotoxicity: Harmful to aquatic organisms, long-term adverse effects in aquatic environment
Aquatic Toxicity Values: LC50 (fish, 96h): 67 mg/L (Pimephales promelas), EC50 (daphnia, 48h): 47 mg/L; toxicity to algae limited studies available
Persistence and Degradability: Slow degradation in water and soil, may persist in environment
Bioaccumulation Potential: Low to moderate (log Kow = 2.1), potential for accumulation in aquatic organisms
Mobility in Soil: Moderately mobile, can leach into groundwater
Other Information: Not considered to be an ozone depleter in typical use but atmospheric breakdown products include inorganic bromides
Waste Disposal Methods: Incinerate at approved facility or dispose of as hazardous waste per local, regional, national, and international regulations
Contaminated Packaging: Rinse containers, dispose as hazardous waste, do not reuse
Precautions for Disposal: Prevent material from reaching drains, sewers, or natural waters, use properly labeled waste containers, comply with EPA, state, or site-specific regulations
Special Instructions: Consult local hazardous waste regulator for appropriate disposal methods for spent material and unused product, keep waste separate from incompatible chemicals
Proper Shipping Name: 1-Bromopropane
UN Number: UN2344
Class: 3 (flammable liquid)
Packing Group: II
Labels Required: Flammable Liquid
Special Precautions: Ship in accordance with DOT, IATA and IMDG regulations, avoid shipping with incompatible goods, ensure containers are securely closed and upright
Environmental Hazards: Marine pollutant status may apply, check local requirements
Transport in Bulk: Subject to MARPOL Annex II and IBC Code for ship bulk handling
US Federal Regulations: TSCA listed, SARA 313 (Section 313 toxic chemical), CERCLA reportable quantity not established, not listed as hazardous air pollutant under CAA
State Regulations: Listed under California Proposition 65 for reproductive toxicity, included in New Jersey RTK, Pennsylvania RTK
International Regulations: EINECS/ELINCS listed, subject to use or concentration restrictions in EU under REACH, regulations may differ by jurisdiction
Other Regulatory Information: Product safety guidelines regularly updated, consult latest national chemical safety codes, users responsible for compliance with all applicable laws
