Product Name: N,N-Dimethylaniline
Synonyms: Dimethylaniline, DMA
Chemical Formula: C8H11N
CAS Number: 121-69-7
Recommended Use: Chemical intermediate, laboratory reagent, dye and pigment manufacture
Manufacturer Details: Refer to distributor or chemical supplier for specific contact information
Emergency Contact: Refer to local poison control center or emergency services for immediate response
Classification: Flammable liquid, acute toxicity (oral, dermal, inhalation), specific organ toxicity
Hazard Pictograms: Flame, skull and crossbones, exclamation mark, health hazard
Signal Word: Danger
Hazard Statements: Highly flammable liquid and vapor, toxic if swallowed, harmful if inhaled, may cause damage to organs through prolonged or repeated exposure, causes skin and eye irritation
Precautionary Statements: Avoid breathing vapors, wear protective equipment, keep container tightly closed, use explosion-proof equipment, wash thoroughly after handling
Potential Health Effects: Central nervous system depression, methemoglobinemia, liver and kidney damage, headache, nausea, dizziness, cyanosis due to blood effect
Environmental Hazard: Toxic to aquatic life with long-lasting effects
Chemical Name: N,N-Dimethylaniline
CAS Number: 121-69-7
Concentration: >99% pure unless otherwise specified
Impurities: Trace amines, phenols, moisture depending on storage condition
Additional Ingredients: None expected at significant concentrations in commercial samples
Inhalation: Move affected person to fresh air, seek medical attention, administer oxygen if breathing is difficult
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water, seek medical attention if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if easy to do, continue rinsing, seek prompt medical attention
Ingestion: Rinse mouth, do not induce vomiting, get medical help immediately, never give anything by mouth to an unconscious person
Most Important Symptoms: Headache, fatigue, cyanotic skin, nausea, respiratory distress, confusion, potential for coma with severe exposure
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray for cooling containers only
Unsuitable Media: Direct water streams may spread burning liquid
Fire and Explosion Hazards: Vapors may form explosive mixtures with air, containers may rupture under heat, combustion produces toxic gases such as nitrogen oxides and carbon monoxide
Special Protective Equipment: Firefighters should use self-contained breathing apparatus, full protective gear
Precautions: Evacuate area, keep cool with water spray, prevent runoff from entering storm drains or waterways
Personal Precautions: Evacuate unnecessary personnel, ensure adequate ventilation, eliminate ignition sources, wear recommended PPE including gloves, safety goggles, chemical resistant clothing
Environmental Precautions: Prevent entry into soil, drains, watercourses, use dikes to contain large spills
Cleanup Methods: Absorb with sand or inert material, collect residue in suitable containers for disposal, ventilate area, wash site after cleanup is complete
Handling: Work in well-ventilated areas or under local exhaust, avoid contact with skin, eyes, and clothing, avoid inhalation of vapor or mist, use spark-proof tools and equipment, ground and bond containers during transfer
Storage: Store in tightly closed containers in a cool, dry, well-ventilated area away from heat sources, direct sunlight, incompatible materials such as acids, oxidizers, and halogens, clearly label containers, restrict access to trained personnel
Hygiene Practices: Wash thoroughly after handling, remove contaminated clothing before entering common areas, do not eat, drink, or smoke in storage or handling areas
Occupational Exposure Limits: OSHA PEL: 5 ppm (skin), ACGIH TLV: 0.5 ppm (skin), consult national standards for permissible limits
Engineering Controls: Use fume hoods or local exhaust, maintain eyewash stations and safety showers nearby
Personal Protective Equipment: Splash goggles, face shield, chemical-resistant gloves (nitrile, neoprene), lab coat or apron, impervious footwear, respiratory protection suited for organic vapors if exposures may exceed the threshold limit
Monitoring: Regular monitoring of vapor concentration in work areas, biological monitoring for methemoglobin as marker of exposure
Appearance: Colorless to light yellow oily liquid
Odor: Aromatic, similar to aniline
Odor Threshold: Not determined precisely, lower than aniline
Melting Point: 2 °C (36 °F)
Boiling Point: 192 °C (378 °F)
Flash Point: 58 °C (136 °F) closed cup
Flammability: Flammable liquid
Vapor Pressure: 0.4 mmHg (20 °C)
Density: 0.956 g/cm³ (20 °C)
Solubility: Miscible with alcohol, ether, limited solubility in water (1.1 g/L at 20 °C)
Partition Coefficient: log Kow: 1.65
Vapor Density: 4.4 (air=1)
Auto-ignition Temperature: 541 °C (1006 °F)
Decomposition Temperature: Not precisely determined
Evaporation Rate: Slower than butyl acetate
Chemical Stability: Stable under recommended conditions, sensitive to light and air, may darken on exposure
Hazardous Reactions: Strong acids and oxidizing agents may initiate violent reactions, peroxides formation risk in prolonged storage
Conditions to Avoid: Heat, open flames, sparks, direct sunlight, contact with incompatible substances
Incompatible Materials: Halogens, strong acids, oxidizers, acyl chlorides, peroxides
Hazardous Decomposition Products: Toxic nitrogen oxides, carbon monoxide, carbon dioxide, possible aniline formation
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 (rat): 616 mg/kg, Dermal LD50 (rabbit): >800 mg/kg, Inhalation LC50 (rat, 4 h): 1.6 mg/L
Chronic Toxicity: Potential cumulative effect on liver, kidneys, hematological system, causes methemoglobinemia, suspected carcinogen in animal studies
Symptoms: Cyanosis, dizziness, headache, vomiting, confusion, respiratory distress, symptoms may be delayed in onset
Sensitization: Not reported in standard tests
Mutagenicity/Carcinogenicity: Limited evidence of mutagenicity in vitro, no conclusive human carcinogenicity data, IARC: Not classified
Repeated Exposure: Central nervous system depression, organ toxicity as indicated by animal studies
Toxicity to Aquatic Life: Acutely toxic, LC50 fish 7.9 mg/L (Oryzias latipes, 96 h), toxic to invertebrates and algae as indicated by laboratory studies
Persistence and Degradability: Partially biodegradable, degradation rate depends on conditions, may persist in soil and water
Bioaccumulation Potential: Moderate as indicated by log Kow value
Mobility in Soil: Low to moderate leaching in soil, risk of groundwater contamination if released
Other Harmful Effects: Harmful to aquatic life even at low concentrations, recommend careful waste handling to prevent entry to environment
Methods of Disposal: Incinerate under controlled conditions at licensed facility, comply with local and national regulations, containers must be triple-rinsed and punctured before disposal
Disposal of Contaminated Packaging: Use hazardous waste procedures, avoid direct disposal into sewers or natural bodies of water
Precautions: Handle according to established chemical waste management protocols, record disposal and handling under hazardous waste manifest
UN Number: UN 2253
Proper Shipping Name: N,N-Dimethylaniline
Hazard Class: 6.1 (Toxic substances)
Packing Group: II
Marine Pollutant: Yes
Special Precautions: Emergency response guide should be available during transport, transportation only permitted in suitable containers with hazardous label, vehicle drivers trained in handling chemical emergencies, follow IATA, IMDG, DOT, ADR regulations for packaging and documentation
Emergency Response: Spill kits, fire extinguishers, safety data should be accessible in transport vehicle
OSHA: Regulated as hazardous substance
TSCA: Listed
SARA Title III: Subject to immediate (acute) and delayed (chronic) health hazard reporting
RCRA: Hazardous waste number U122
California Proposition 65: Contains chemicals known to the State of California to cause cancer
WHMIS (Canada): D1B (Toxic material), B2 (Flammable liquid)
Other Standards: Workplace labelling required, use of personal protective equipment mandated, country-specific regulations may apply
International Regulations: Covered under PIC (Prior Informed Consent) procedure for trade, subject to strict environmental control and reporting in Europe, Asia, North America
