Product Name: N-Methylmethanesulfonamide
Synonyms: Methyl(methylsulfonyl)amine
Chemical Formula: C2H7NO2S
CAS Number: 13260-96-5
Manufacturer: [Manufacturer Name], [Full Address], [Emergency Phone Number]
Recommended Use: Chemical intermediate, Research and development
Restrictions: Industrial use only, not for food, drug, or household
GHS Classification: Skin irritant (Category 2), Eye irritant (Category 2A), Acute toxicity, Oral (Category 4)
Signal Word: Warning
Hazard Statements: Causes skin irritation, causes serious eye irritation, harmful if swallowed
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, use protective gloves/eye protection
Other Hazards: Contact can aggravate pre-existing skin or eye conditions, not classified as flammable, but reacts with strong oxidizers
Chemical Name: N-Methylmethanesulfonamide
Concentration: ≥ 98%
Impurities: Water (< 1%), Organic trace residuals (< 0.5%)
Molecular Weight: 109.15 g/mol
EINECS Number: 236-238-7
Structure: CH3SO2NHCH3
Inhalation: Move to fresh air immediately, if breathing is difficult, oxygen support from trained personnel
Skin Contact: Remove contaminated clothing and rinse skin with running water for at least 15 minutes, seek medical attention for persistent irritation
Eye Contact: Rinse cautiously with water for 15-20 minutes, remove contact lenses if easy to do, get medical care if irritation continues
Ingestion: Rinse mouth, do not induce vomiting unless advised by medical personnel, call a poison center
Most Important Symptoms: Stinging, redness, discomfort, nausea, possible headache
Medical Attention: If symptoms persist or worsen, immediate care needed especially if swallowed in large quantities
Suitable Extinguishing Media: Foam, dry chemical, carbon dioxide, water spray, do not use direct jet of water
Specific Hazards: Toxic fumes on combustion include oxides of carbon, nitrogen, sulfur, methylamine, and sulfur dioxide
Protective Equipment: Chemical-resistant suit, self-contained breathing apparatus in confined spaces
Advice for Firefighters: Use water spray to cool unopened containers, approach upwind to avoid hazardous vapors, prevent run-off water from entering waterways
Personal Precautions: Ventilate area, do not touch spilled material without protection, wear gloves, goggles, and NIOSH-approved respirator if dust or vapor risk
Environmental Precautions: Prevent release to soil, sewers, surface, or groundwater, notify authorities if significant spill enters environment
Methods for Clean Up: Collect spilled solid with shovel, sweep up carefully, place in clearly labeled container for disposal, wash spill area with water and neutral detergent
Safe Handling: Use in fume hood or well-ventilated area, avoid skin and eye contact, avoid generating dust or aerosols, do not eat, drink, or smoke while handling, keep containers tightly closed
Storage Conditions: Store in original container in cool, dry, well-ventilated place, away from heat sources, incompatible materials like strong oxidizing agents
Special Requirements: Keep away from food, feed, incompatible substances, separate from acids, base, and oxidizing chemicals
Exposure Limits: No regulatory limits assigned; handle as nuisance dust if airborne
Engineering Controls: Use local exhaust or general room ventilation, safety shower and eyewash accessible
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), chemical splash goggles, laboratory coat, if risk of inhalation, use respirator with organic vapor cartridge
General Hygiene: Wash hands before breaks and after handling, remove contaminated clothing, launder before reuse
Appearance: White to off-white crystalline solid
Odor: Slight amine odor
Odor Threshold: Not available
Melting Point: 78 – 83°C
Boiling Point: Not established, decomposes before boiling
Solubility: Readily soluble in water, soluble in methanol, ethanol
Density: Approximately 1.20 g/mL at 20°C
Vapor Pressure: Negligible at room temperature
pH: Neutral (in water)
Partition Coefficient: log Kow ~ -1.2 (estimated)
Flash Point: Above 100°C (not easily ignitable)
Evaporation Rate: Not volatile
Autoignition Temperature: Not established
Chemical Stability: Stable under normal ambient conditions, can decompose at high temperatures, keep away from heat sources
Reactivity: Incompatible with strong oxidizing agents, acids, and bases; may react with halogenated compounds
Hazardous Decomposition Products: Produces methylamine, sulfur dioxide, nitrogen oxides, carbon monoxide under fire conditions
Polymerization: No dangerous polymerization expected under proper storage and use
Acute Toxicity: Oral LD50 (rat) estimated > 500 mg/kg, limited data
Skin Corrosivity: May cause local irritation on contact
Eye Effects: Moderately irritating, redness and discomfort
Respiratory Effects: Exposure to dust or vapors leads to coughing, sore throat, headache in sensitive individuals
Chronic Effects: Prolonged or repeated contact may cause dermatitis, no evidence for carcinogenicity or mutagenicity
Sensitization: Not expected based on structure, use precaution until further data
Target Organs: Skin, eyes, gastrointestinal if ingested
Ecotoxicity: Low expected acute aquatic toxicity, not expected to bioaccumulate (low log Kow)
Aquatic Impact: Water-soluble, small spills dilute quickly, large releases threaten aquatic invertebrates
Persistence and Degradability: Biodegradable by microorganisms in soil and water
Mobility in Soil: High solubility means it can migrate, risk to groundwater in significant spills
Other Effects: Discharge to environment must comply with local regulations, not classified as marine pollutant
Waste Treatment Methods: Dispose of as hazardous chemical waste, do not pour down drain, send to licensed chemical disposal facility
Contaminated Packaging: Containers must be triple rinsed, label as chemical waste
Local Regulations: Confirm with environmental authorities, small laboratory quantities may qualify for special disposal programs
UN Number: Not assigned
Transport Hazard Class: None regulated
Packing Group: Not assigned
Special Transport Precautions: Ship in robust, leak-proof containers, clearly identified, avoid shipment with acids or oxidizers, prevent moisture and heat exposure
DOT/IATA/IMDG: N-Methylmethanesulfonamide not classified as dangerous for transport under these codes
US TSCA: Listed
EU REACH: Substance registration may apply above threshold, consult supplier
SARA 311/312: Classified for acute health hazard (irritant)
California Proposition 65: Not listed as carcinogen or reproductive toxicant
Other Regulatory Info: Subject to workplace exposure and safety standards, not regulated as controlled substance, check national and local chemical inventories for status
