Product Name: Laurocapram
Synonyms: 1-Dodecylazacycloheptan-2-one, Azone
CAS Number: 59227-89-3
Recommended Use: Used as a skin penetration enhancer, typically in cosmetics, pharmaceuticals, transdermal delivery systems.
Manufacturer/Supplier: Contact chemical supplier or distributor for current details.
Emergency Contact: Local emergency services or national poison centre.
GHS Classification: Not classified as hazardous under GHS criteria.
Physical Hazards: No particular physical danger recognized.
Health Hazards: May cause slight irritation if skin or eye contact occurs. Inhalation of mists or vapors could cause respiratory discomfort. Ingestion unlikely to be serious in small quantities but could lead to gastrointestinal discomfort.
Environmental Hazards: No adverse environmental effects anticipated under normal conditions of use.
Label Elements: None required.
Signal Word: None.
Hazard Statements: Not hazardous.
Precautionary Statements: Avoid prolonged contact with skin. Prevent eye exposure. Use adequate ventilation.
Chemical Identity: Laurocapram
CAS Number: 59227-89-3
Concentration: ≥98% (pure substance)
Impurities: No significant impurities considered to impact classification.
Molecular Formula: C18H35NO
Eye Contact: Rinse carefully with plenty of water for at least 10 minutes, lifting upper and lower eyelids occasionally. Remove contact lenses if present and easy. Seek medical advice if irritation develops.
Skin Contact: Remove contaminated clothing. Wash exposed area with copious water and mild soap. If irritation appears or persists, consult a physician.
Inhalation: Remove individual to fresh air. Seek medical attention if symptoms such as coughing or discomfort persist.
Ingestion: Rinse mouth thoroughly. Drink water to dilute. Avoid inducing vomiting without advice from medical personnel. If feeling unwell, contact a doctor or poison center.
Suitable Extinguishing Media: Use dry chemical powder, foam, water spray, or carbon dioxide.
Unsuitable Extinguishing Media: Direct water jet may spread burning material.
Specific Hazards: Product may emit nitrogen oxides and carbon oxides if heated strongly or burned.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear.
Special Procedures: Cool exposed containers with water spray. Avoid inhaling combustion products.
Personal Precautions: Wear appropriate personal protective equipment (PPE) such as gloves and goggles. Prevent skin and eye contact.
Environmental Precautions: Prevent entry to sewers, surface, or underground water. Notify authorities if significant spillage threatens the environment.
Methods for Cleanup: Absorb spills with inert material (sand, earth, diatomite). Place in containers for disposal according to local regulations. Wash contaminated surfaces with water and detergent, making sure all residues are collected.
Ventilation: Ventilate the area to remove vapors.
Safe Handling: Use with adequate ventilation. Minimize contact with skin and eyes. Do not eat, drink, or smoke during use. Practice good personal hygiene.
Storage Requirements: Store tightly closed in original container in a cool, dry, well-ventilated place. Keep away from incompatible materials, strong acids, and oxidizing agents. Protect from excessive heat and direct sunlight.
Special Precautions: Do not reuse empty containers. Ensure good housekeeping to prevent accidental exposures.
Occupational Exposure Limits: No specific exposure limits established.
Engineering Controls: Provide adequate general or local exhaust ventilation. Work in a fume hood if aerosol generation likely.
Personal Protective Equipment: Use nitrile or neoprene gloves, chemical splash goggles, and lab coat. Use a respirator if exposure to vapors or dust above nuisance levels is possible.
Hygiene Measures: Wash hands and forearms thoroughly after handling. Do not bring contaminated clothes into personal spaces.
Appearance: Clear, colorless to pale yellow oily liquid.
Odor: Faint, characteristic.
Odor Threshold: Not established.
pH: Not applicable.
Melting Point: 22-25°C
Boiling Point: 168-170°C at 2 mmHg
Flash Point: >150°C (closed cup)
Evaporation Rate: Not available.
Flammability: Not easily ignitable.
Vapor Pressure: <0.01 mmHg at 20°C
Vapor Density: >1 (air = 1)
Solubility: Insoluble in water; miscible with most organic solvents.
Partition Coefficient (log Kow): approx. 6.2
Decomposition Temperature: Data not available.
Viscosity: Not available.
Density: 0.95-0.96 g/cm³ at 25°C
Chemical Stability: Stable at normal temperatures and storage conditions.
Incompatible Materials: Strong acids, bases, oxidizing agents.
Conditions to Avoid: Prolonged exposure to heat, direct sunlight, open flames, or sources of ignition.
Hazardous Decomposition Products: Burning produces carbon monoxide, carbon dioxide, nitrogen oxides.
Hazardous Reactions: No hazardous polymerization expected.
Acute Toxicity: No known acute toxicity at reasonable exposure. Oral LD50 (rat) > 5000 mg/kg indicating low toxicity.
Skin Corrosion/Irritation: Potential mild irritant to skin after prolonged or repeated contact.
Eye Damage/Irritation: May cause mild irritation.
Respiratory Sensitization: Not expected to be a respiratory sensitizer.
Skin Sensitization: Generally not recognized as a skin sensitizer.
Germ Cell Mutagenicity/Carcinogenicity: No data on mutagenicity or carcinogenicity in humans or animals. Not listed as a carcinogen by IARC, NTP, or OSHA.
Reproductive Toxicity: No known adverse reproductive effects.
Specific Target Organ Toxicity: No data suggesting harmful effects.
Information on Likely Routes of Exposure: May enter body via ingestion, inhalation, or skin absorption if precautions ignored.
Ecotoxicity: Limited information available; not expected to be highly toxic to aquatic organisms at typical environmental concentrations.
Persistence and Degradability: Expected to degrade slowly in soil and water.
Bioaccumulative Potential: High log Kow suggests potential for bioaccumulation.
Mobility in Soil: Substance considered moderately mobile due to physico-chemical properties.
Other Adverse Effects: No specific data on ozone depletion, photochemical ozone creation, endocrine disruption.
Disposal Methods: Incinerate in an approved facility, or dispose through standard chemical waste procedures following local regulations. Do not pour into drains or waterways.
Contaminated Packaging: Dispose of as unused product if not thoroughly cleaned. Comply with all waste handling and transport requirements.
European Waste Catalogue (EWC) Code: 07 07 99 (wastes not otherwise specified)
Special Instructions: Seek professional waste services when handling significant quantities.
UN Number: Not regulated.
Proper Shipping Name: Not regulated as hazardous material for any mode of transport.
Transport Hazard Class: Not classified.
Packing Group: Not assigned.
Environmental Hazards: None identified.
Special Precautions for Transport: Prevent leaks or damage during transport. Keep containers sealed and upright.
TSCA Inventory (US): Listed.
EINECS/ELINCS (EU): Listed (261-668-9).
DSL/NDSL (Canada): Listed.
REACH Status (EU): Registered or exempt from registration.
OSHA Hazard Communication Standard: Not classified as hazardous.
California Proposition 65: Not listed.
Other Local Regulations: Consult local authorities for applicable workplace limits and restrictions.
