Product Name: Bromotrimethylsilane
Chemical Formula: C3H9BrSi
CAS Number: 2857-97-8
Synonyms: Trimethylsilyl bromide
Recommended Use: Laboratory reagent, intermediate in organic synthesis
Manufacturer: [Obtain from supplier label]
Emergency Phone Number: [Check supplier documentation or SDS provider]
GHS Classification: Flammable liquids (Category 2), Acute toxicity, inhalation (Category 3), Skin corrosion/irritation (Category 1B)
Signal Word: Danger
Hazard Statements: Highly flammable liquid and vapor. Causes severe skin burns and eye damage. Toxic if inhaled.
Pictograms: Flame, skull and crossbones, corrosion
Precautionary Statements: Avoid breathing vapors. Use only non-sparking tools. Keep container tightly closed. Wash thoroughly after handling.
Chemical Name: Bromotrimethylsilane
Concentration: 98-100%
Impurities: Trace impurities may remain from synthesis, consult supplier for details
Stabilizing Additives: None reported by principal manufacturers
Inhalation: Move person to fresh air. Seek medical attention if symptoms such as coughing, dizziness, or breathing issues develop.
Skin Contact: Remove contaminated clothing. Immediately rinse skin with plenty of water for at least 15 minutes. Seek urgent medical attention.
Eye Contact: Rinse eyes cautiously with water for several minutes. Remove contact lenses if possible. Continue rinsing and get medical aid.
Ingestion: Do not induce vomiting. Rinse mouth with water. Give nothing by mouth if patient is unconscious. Contact poison control or physician immediately.
Most Important Symptoms: Burns, respiratory irritation, severe pain, eye damage
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical powder, CO2. Avoid water—it may intensify release of toxic gases.
Specific Hazards Arising from Chemical: Releases hazardous vapors including hydrogen bromide and methyl bromide when exposed to flames.
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective gear. Fight fire from safe distance or protected location.
Advice for Firefighters: Prevent runoff from entering drains or watercourses. Use water spray for cooling exposed containers only.
Personal Precautions: Evacuate unnecessary personnel. Wear protective gloves, chemical splash goggles, and respirators suitable for organic vapors.
Environmental Precautions: Prevent spillage from reaching soil, surface waters, or drains. Inform authorities if large releases occur.
Methods for Containment: Absorb with dry sand or inert material. Do not use water for cleanup as it may react dangerously.
Cleanup Procedures: Collect material in sealed, clearly labeled containers for disposal by licensed contractor.
Handling: Work in a well-ventilated chemical fume hood. Avoid contact with skin, eyes, and clothing. Keep containers closed except during transfer.
Storage: Store in a cool, dry, ventilated area away from heat and ignition sources. Keep away from incompatible materials including water, strong bases, and oxidizers. Store in tightly sealed original containers, with proper secondary containment.
Special Precautions: Ground and bond containers during transfer.
Occupational Exposure Limits: No specific OSHA or ACGIH limits for bromotrimethylsilane; minimize exposure by engineering controls.
Engineering Controls: Use chemical fume hoods, process enclosures, or local exhaust ventilation.
Personal Protective Equipment: Chemical-resistant gloves (butyl or nitrile rubber), flame-retardant lab coat, splash-proof goggles, suitable respirator when airborne concentrations exceed recommended exposure.
Hygiene Measures: Wash hands and face before breaks, after handling. Remove soiled clothing and clean before reuse.
Appearance: Clear, colorless to faint yellow liquid
Odor: Sharp, irritating
Melting Point: -62°C
Boiling Point: 101°C
Flash Point: 7°C
Auto-ignition Temperature: 230°C
Vapor Pressure: 30 hPa (20°C)
Solubility: Reacts with water
Density: 1.18 g/cm³ (20°C)
pH: Not determined
Partition Coefficient: Not available
Chemical Stability: Stable under recommended storage conditions, but hydrolyzes rapidly on contact with water releasing corrosive hydrogen bromide.
Reactivity: Highly reactive with water, alcohols, acids, and bases.
Hazardous Decomposition Products: Hydrogen bromide, methyl bromide, silicon oxides.
Incompatible Materials: Moisture, strong oxidizing agents, alkalis.
Conditions to Avoid: Heat, flames, sparks, direct sunlight, humid air.
Acute Toxicity: Inhalation, skin, and eye contact cause serious chemical burns. Inhalation may be fatal in high concentrations.
Chronic Effects: Repeated exposure may damage respiratory tract, eyes, and skin.
Routes of Exposure: Inhalation, skin absorption, ingestion, eye contact.
Symptoms: Burns, coughing, shortness of breath, blistering, possible pulmonary edema.
Carcinogenicity: No evidence found in available studies.
Other Data: No significant data on reproductive toxicity or mutagenicity.
Ecotoxicity: Harmful to aquatic life due to formation of hydrogen bromide and siloxanes.
Persistence and Degradability: Hydrolyzes rapidly in water; breakdown products persist in environment.
Bioaccumulative Potential: Low expected due to rapid transformation.
Mobility in Soil: High; migrates quickly through water due to reactivity.
Other Harmful Effects: May contribute to acidification of water bodies.
Waste Disposal Methods: Incineration in licensed chemical incinerator after mixing with suitable combustible absorbent. Do not pour down the drain.
Contaminated Packaging: Dispose of as unused material. Rinse thoroughly with a suitable neutralizing agent under expert supervision.
Precautions: Comply with local, regional, and national regulations. Avoid disposal in sewage or surface water.
UN Number: 1993
UN Proper Shipping Name: Flammable Liquid, N.O.S. (Bromotrimethylsilane)
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: II
Marine Pollutant: Yes
Special Precautions for User: Use UN-approved containers, provide clear hazard markings, avoid physical shocks during transit.
Regulatory Notes: Check for additional regional or international shipping restrictions.
Safety, Health & Environmental Regulations: Subject to OSHA hazardous chemical requirements. Registered under TSCA in the United States.
Other Regulatory Listings: Check local SARA Title III, CERCLA, REACH, and Canadian WHMIS regulations.
Labeling Requirements: GHS-compliant signal word “Danger,” hazard pictograms, recommended PPE symbols.
Additional Guidance: Employers must provide training and access to Safety Data Sheets. Updated SDS documents needed for regular review and employee safety programs.
