Product Name: 5-Bromo-2-Fluoro-4-Methylaniline
Synonyms: 4-Methyl-5-Bromo-2-Fluoroaniline
CAS Number: 885276-46-4
Recommended Use: Organic synthesis, research applications
Manufacturer: Chemical manufacturing firms specializing in advanced intermediates
Supplier Details: Supply platforms for laboratory reagents
Emergency Contact: National chemical emergency lines, poison control center
Address: Relevant laboratory or distributor office address listed on the shipment documentation
GHS Classification: Harmful if swalled, skin and serious eye irritant, suspected of causing genetic defects
Signal Word: Warning
Hazard Statements: H302: Harmful if swallowed, H315: Causes skin irritation, H319: Causes serious eye irritation, H340: May cause genetic defects
Pictograms: Exclamation mark, health hazard
Precautionary Statements: Wear protective gloves, clothing, eye and face protection, avoid release to the environment, do not eat or drink during handling, wash hands thoroughly after use
Routes of Exposure: Inhalation, ingestion, skin, eyes
Symptoms: Skin or eye redness, itching or discomfort, throat irritation, gastrointestinal upset
Aggravated Conditions: Skin disorders, respiratory conditions could increase risk
Chemical Name: 5-Bromo-2-Fluoro-4-Methylaniline
Molecular Formula: C7H7BrFN
CAS Number: 885276-46-4
Concentration: Pure compound or as stated on label
Impurities/Additives: Levels considered negligible for laboratory use, refer to batch-specific CoA for details
Inhalation: Move to fresh air, keep person comfortable, seek medical attention for persistent symptoms
Skin Contact: Remove contaminated clothing, rinse skin with water for at least 15 minutes, seek medical advice for irritation
Eye Contact: Flush eyes with water for several minutes, remove contact lenses after first minute, continue to irrigate, get medical help if discomfort continues
Ingestion: Rinse mouth, do not induce vomiting, seek urgent medical care
Most Important Symptoms: Redness, swelling, discomfort in affected areas, nausea, headache
Notes for Medical Personnel: Treat symptomatically, provide supportive measures
Suitable Extinguishing Media: Dry chemical powder, CO₂, alcohol-resistant foam, water spray
Unsuitable Media: Straight streams of water might spread chemical
Special Hazards: Combustion may release toxic fumes including hydrogen bromide, hydrogen fluoride, nitrogen oxides
Protective Equipment: Firefighters need self-contained breathing apparatus, full protective gear
Advice for Firefighters: Evacuate area, fight from safe distance, use water spray to cool containers
Explosion Hazards: No typical explosive properties recorded, but hazardous decomposition products may evolve
Personal Precautions: Evacuate non-essential personnel, ventilate area, avoid contact, use PPE including gloves, goggles, lab coat
Environmental Precautions: Prevent from entering waterways, sewers, soil
Methods for Containment: Contain spill with inert absorbent material like sand, avoid spreading
Cleanup Procedures: Scoop up, place in suitable, labeled waste container, decontaminate spill surface with detergent solution, dispose of according to regulations
Reference For Emergency Responders: See exposure controls for recommended PPE
Precautions: Handle in fume hood or well-ventilated area, avoid direct contact, use PPE
Safe Handling: Transfer with tools or dispensers to minimize release, keep away from food and drinks
Storage Conditions: Store in tightly closed containers, in a dry, cool, well-ventilated area, away from incompatible substances, protect from moisture
Storage Class: Flammable solids, hazardous organic compounds
Incompatible Materials: Strong oxidizers, acids, bases
Occupational Exposure Limits: No established exposure limits; use best laboratory hygiene
Engineering Controls: Use well-ventilated exhaust systems, fume hood
Respiratory Protection: Approved mask with filter for organic vapors if exposure risk exists
Skin Protection: Wear chemical-resistant gloves (e.g., nitrile), laboratory coat
Eye Protection: Chemical safety goggles, face shield if risk of splashes
General Hygiene: Wash hands and face after work, remove soiled clothing and wash before reuse
Appearance: Light tan to brown solid
Odor: Not distinctly noted in available literature
Melting Point: 55-60°C
Boiling Point: Data not readily available
Solubility: Slightly soluble in water, soluble in organic solvents (ethanol, DMSO)
Density: Approximate value found in typical aromatic amines, specific value consult CoA
Vapor Pressure: No reliable data from public safety records
Flash Point: Data not confirmed, anticipated to be moderate for an aromatic amine
Partition Coefficient (log Pow): Not listed
Refractive Index: Not measured
pH: Not applicable, solid compound
Chemical Stability: Stable under standard handling and storage conditions
Conditions to Avoid: Moisture, excessive heat, open flames
Incompatible Materials: Strong oxidizers, strong acids or bases
Hazardous Decomposition Products: Hydrogen bromide, hydrogen fluoride, nitrogen oxides, carbon oxides possible upon combustion or thermal decomposition
Reactivity: Not expected to undergo hazardous reactions under normal laboratory conditions
Acute Toxicity: Oral LD50 expected to fall in low/moderate range, not specifically known; reference similar compounds
Skin Corrosion/Irritation: May cause irritation, redness, discomfort
Serious Eye Damage: Known to cause eye irritation, watering, stinging
Respiratory Sensitization: May cause throat and airway irritation if dust or vapors inhaled
Germ Cell Mutagenicity: Classified as suspected of genetic defects by GHS
Carcinogenicity: No data connecting this compound directly to cancer in humans
Reproductive Toxicity: Not established, exercise caution
Target Organs: Eyes, skin, respiratory tract
Repeated Dose Toxicity: Limited data; precautionary avoidance of chronic exposure advised
Toxicity: No targeted studies; aromatic amines known to be hazardous to aquatic life, avoid release to environment
Persistence and Degradability: Expected to degrade slowly, aromatic compounds can be persistent in environment
Bioaccumulation Potential: Moderate to high based on structural analogs
Mobility in Soil: Slightly mobile due to low water solubility
Other Effects: Possible negative impact on microorganisms in water systems
Disposal Methods: Hand over solid or solutions to licensed hazardous waste disposal contractor; follow applicable regulations
Container Disposal: Decontaminate or triple rinse, render unusable before discarding with hazardous waste
Environmental Precautions: Do not dispose with household waste or down the drain
Waste Code: Assign based on local hazardous waste listing for halogenated organics
Special Precautions: Handle all residues as hazardous
UN Number: Not assigned for this specific compound, handle as hazardous laboratory chemical
Transport Hazard Class: Not classified by DOT, IATA or IMDG for this compound, default to hazardous organic, UN 2811 or similar if bulk quantity
Packing Group: III (expected for low acute toxicity solid organics)
Labeling Requirements: Marked as laboratory reagents, “Harmful, Irritant” as needed
Environmental Hazards: Not a marine pollutant by standard regulations, avoid spillage
Special Transport Precautions: Package in tightly sealed container, protected from physical damage, accompanied by standard shipping documents
Inventory Status: Not listed on TSCA, DSL, EINECS, or other global inventories as bulk chemical, produced primarily for research
Workplace Classification: Subject to laboratory chemical safety guidelines, control exposure limits where possible
Labeling: Requires GHS-compliant labeling with hazard and precaution statements
OSHA: Not regulated as specific hazardous material, general lab safety rules apply
REACH: Not registered for market beyond R&D in the EU
Other Local Regulations: Users need to consult state and municipal chemical restriction lists since local controls sometimes cover specific halogenated compounds
