Product Name: 4,4'-Dihydroxydiphenyl Ether
SYNONYMS: Bisphenol F, DPE, 4,4'-Oxydiphenol
CAS Number: 80-51-3
Manufacturer/Supplier: Chemical supply laboratories or bulk chemical manufacturers, address and contact details as per packaging.
Recommended Use: Starting material for organic syntheses, intermediates for resins, pharmaceuticals, and specialty chemicals.
Classification: Eye Irritation; Skin Sensitization; Specific Target Organ Toxicity (Single Exposure); Not classified as flammable or explosive under GHS.
Signal Word: Warning
Hazard Statements: Causes skin and eye irritation. May cause allergic skin reaction. Harmful if swallowed or inhaled.
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust. Wear protective gloves, eye and face protection. Wash hands thoroughly after handling. Do not eat, drink, or smoke when using this chemical. If skin irritation or rash occurs, seek medical attention.
Chemical Name: 4,4'-Dihydroxydiphenyl Ether
CAS Number: 80-51-3
EC Number: 201-283-8
Percentage: 98% minimum purity
Impurities: Trace levels of residual solvents, unreacted starting materials below 2% combined.
Eye Contact: Rinse immediately with plenty of clean water for at least 15 minutes. Hold eyelids apart. Remove contact lenses if present and easy to do. Seek medical attention.
Skin Contact: Wash thoroughly with soap and warm water. Remove contaminated clothing. Get medical attention if irritation develops.
Inhalation: Remove victim to fresh air and keep at rest. Seek medical advice if symptoms persist.
Ingestion: Rinse mouth with water. Do not induce vomiting. Seek immediate medical advice.
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide.
Unsuitable Extinguishing Media: No known restrictions.
Specific Dangers: Combustion produces toxic vapors including carbon monoxide, carbon dioxide, and phenolic compounds.
Protective Equipment for Firefighters: Self-contained breathing apparatus (SCBA), full protective clothing.
Special Procedures: Move containers from fire area if safe. Cool containers exposed to flames with water spray.
Personal Precautions: Evacuate unnecessary personnel. Avoid dust generation. Ventilate area.
Personal Protective Equipment: Chemical goggles, gloves, impervious clothing.
Environmental Precautions: Prevent further leakage or spillage if safe. Do not discharge into drains, surface water, or soil.
Spill Clean-Up: Sweep or vacuum material using tools that minimize dust generation. Store collected material in properly labeled containers.
Handling: Minimize dust formation. Avoid breathing dust or vapor. Use only in well-ventilated areas.
Storage: Keep in a dry, cool, well-ventilated place. Store in tightly closed original container. Avoid exposure to humidity and direct sunlight.
Incompatible Materials: Strong oxidizers, strong acids, bases.
Hygiene Practices: Wash hands after use. Remove contaminated clothing before entering eating areas.
Occupational Exposure Limits: Not established specifically for this compound by OSHA, NIOSH, or ACGIH.
Engineering Controls: Local exhaust or general room ventilation.
Respiratory Protection: Dust mask or particulate respirator if ventilation is inadequate.
Eye Protection: Safety goggles with side shields.
Skin Protection: Chemical-resistant gloves, long-sleeve laboratory coats or aprons.
Physical State: Crystalline solid
Color: White to off-white
Odor: Phenolic
Melting Point: 172-176°C
Boiling Point: Decomposes before boiling
Solubility in Water: Low (slightly soluble)
Density: 1.27 g/cm³
Vapor Pressure: Negligible at room temperature
Flash Point: >160°C
Partition Coefficient n-octanol/water (log Pow): 2.5 (estimated)
pH: Not applicable (solid)
Chemical Stability: Stable under normal storage and handling conditions.
Reactivity: Not reactive under ordinary conditions.
Hazardous Reactions: Reacts with strong oxidizing agents.
Hazardous Decomposition Products: Phenol, carbon dioxide, carbon monoxide.
Conditions to Avoid: Exposure to moisture, excessive heat.
Acute Toxicity: LD50 (oral, rat): 512 mg/kg; LD50 (dermal, rabbit): >2000 mg/kg.
Irritation/Corrosion: Moderate irritant to eyes and skin (based on animal studies and structure-activity relationship).
Skin Sensitization: May cause allergic reaction after prolonged or repeated contact.
Inhalation: Prolonged exposure to dust may cause respiratory irritation.
Chronic Effects: No data indicating carcinogenic, mutagenic, or reproductive effects; considered of low systemic toxicity.
Ecotoxicity: Expected to have moderate aquatic toxicity; LC50 (fish, 96h): 6.8 mg/L.
Persistence and Degradability: Not readily biodegradable in standard tests.
Bioaccumulation Potential: Moderate, based on partition coefficient.
Mobility in Soil: Low to moderate, depending on local conditions.
Other Adverse Effects: Large spills may pose local hazard to aquatic life.
Waste Treatment Methods: Incinerate under controlled conditions or send to licensed chemical waste facility.
Container Disposal: Triple rinse, then puncture or crush and dispose by an approved method.
Do Not Release: Do not discharge unused material into drains, watercourses, or onto the ground.
UN Number: Not classified as hazardous for transport by road, rail, sea, or air.
Proper Shipping Name: Not regulated.
Hazard Class: None assigned.
Packing Group: Not applicable.
Environmental Hazards: Not a marine pollutant based on available information.
Inventory Status: Listed on TSCA (US), EINECS (EU), DSL (Canada), ENCS (Japan), and other national inventories.
SARA Title III: Not listed under Section 302, 304, or 313.
OSHA: Not specifically regulated as a hazardous material.
WHMIS Classification (Canada): D2B (Toxic Material Causing Other Toxic Effects).
REACH Status (EU): Registered or pre-registered for relevant uses.
