Chemical Name: 3-Iodo-2-propynyl butylcarbamate
Trade Names: IPBC, Carbamic acid, butyl-, 3-iodo-2-propynyl ester
CAS Number: 55406-53-6
Use: Industrial preservative and fungicide, widely found in paints, wood preservatives, and personal care products
Manufacturer Information: Manufacturer details and emergency contact information should appear on the label. Responsible parties maintain emergency call lines for spill and medical advice.
GHS Classification: Acute Toxicity (Oral) Category 4, Skin Sensitization Category 1, Eye Irritation Category 2A, Hazardous to the Aquatic Environment (Chronic) Category 1
Signal Word: Warning
Hazard Statements: Causes skin and serious eye irritation, may cause an allergic skin reaction, harmful if swallowed, very toxic to aquatic life with long-lasting effects
Pictograms: Exclamation mark, environment
Precautions: Avoid skin and eye contact, wear chemical-resistant gloves, goggles, and suitable protective clothing; prevent release into the environment; do not breathe dust or mist.
Substance: 3-Iodo-2-Propynyl Butylcarbamate
Chemical Formula: C8H12INO2
Purity: Typically over 95% active ingredient
Impurities: Levels depend on supplier; minor solvent residues or reaction by-products may appear
Other Additives: Formulated products may contain surfactants, solvents, stabilizers based on application requirement
General Advice: Move exposed individual to fresh air, keep warm and at rest
Inhalation: Remove to fresh air, monitor for respiratory distress; medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, wash skin thoroughly with water and soap, do not use solvents
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical attention
Ingestion: Rinse mouth, do not induce vomiting, call poison center or physician for guidance
Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or foam
Excluded Media: Direct water jet may spread chemical
Fire Hazards: Emits toxic iodine, nitrogen oxides, carbon oxides upon combustion
Protective Equipment: Firefighters should wear self-contained breathing apparatus, fully protective gear
Advice: Evacuate area, prevent contaminated water runoff
Personal Precautions: Avoid dust formation, ensure adequate ventilation, use personal protective equipment as recommended
Environmental Precautions: Prevent entry into drains, waterways, soil
Spill Cleanup: Scoop or shovel spilled solid into labelled waste container; for liquid, soak with inert absorbent material, collect and dispose in accordance with local regulations
Disposal: Follow spill waste handling protocols, avoid flushing with water, decontaminate equipment
Handling: Handle in well-ventilated areas, avoid inhalation and contact with skin, eyes, or clothing, wash hands after use
Mechanical Precautions: Use equipment resistant to corrosion, earth containers against static discharge where flammable solvents are present
Hygiene Practices: No eating, drinking, or smoking during use, personal protective clothing required
Storage: Store tightly closed in original container, cool, dry, well-ventilated area away from food, feed, incompatible substances (strong oxidizers, acids, bases), and sunlight
Shelf Life: Maintain below 30°C; do not store near heat sources
Control Parameters: National authorities may set recommended or permissible exposure limits—consult government guidance
Engineering Controls: Local exhaust or general ventilation, avoid formation of aerosols
Personal Protection: Gloves (nitrile or neoprene), safety goggles or face shield, chemical-resistant protective clothing, suitable respiratory protection for dusty environments
Work Practices: Maintain eye wash stations and safety showers, practice regular laundering of workwear
Appearance: White to off-white crystalline powder
Odor: Faint chemical
Melting Point: 65–70°C
Boiling Point: Decomposes before boiling
Solubility: Sparingly soluble in water, more soluble in organic solvents like acetone and alcohols
Vapor Pressure: Very low at room temperature
Relative Density: 1.65–1.7 g/cm³
Partition Coefficient: log Pow around 2.8
Stability: Stable under recommended conditions, avoid excessive heat/light
Reactivity: May react with strong acids, bases, oxidizing agents
Chemical Stability: Resistant to hydrolysis at neutral/acidic pH, slowly degrades at higher pH or temperature
Conditions to Avoid: Direct sunlight, heat, moisture, incompatible substances
Hazardous Decomposition: Releases iodine, carbon oxides, nitrogen oxides if burned
Polymerization: Does not polymerize under recommended handling procedures
Acute Oral Toxicity: LD50 (rat, oral): 1,000–1,500 mg/kg
Acute Dermal Toxicity: LD50 (rabbit, dermal): >2,000 mg/kg
Skin Irritation: Causes irritation, may cause allergic response
Eye Irritation: Causes moderate to severe irritation
Inhalation: May cause respiratory irritation if dust or vapor generated
Sensitization: Skin sensitizer, repeated contact increases risk
Chronic Effects: No evidence of carcinogenicity at low exposure; high doses, animal studies show thyroid and hepatic effects
Mutagenicity: Not classified as mutagenic; data gaps remain
Reproductive Toxicity: No significant findings under typical exposure
Ecotoxicity: Very toxic to aquatic organisms, fish LC50 (96 hr): 0.067 mg/L (Oncorhynchus mykiss), Daphnia EC50 (48 hr): 0.16 mg/L
Persistence and Degradability: Moderately persistent, slowly biodegradable, can accumulate in aquatic environment
Bioaccumulative Potential: Moderate potential due to log Pow; limited in higher organisms
Mobility in Soil: Low mobility; binds to organic matter
Other Effects: Long-term aquatic toxicity remains a concern; regulatory restrictions in some countries
Waste Treatment: Dispose of material in accordance with local, regional, and national regulations
Recommended Disposal Method: Incineration in approved facilities, do not landfill large amounts
Container Handling: Completely empty containers before discarding, avoid reuse; triple rinse and puncture
Do Not: Flush into surface water, sewer systems, or soil
UN Number: 3077
UN Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (contains IPBC)
Transport Hazard Class: Class 9—Miscellaneous dangerous substances and articles
Packing Group: III (minor hazard)
Marine Pollutant: Yes
Special Precautions: Keep away from food and feed; apply spill control in case of accident; check specific guidance for your region
EU Classification: Classified as hazardous under Regulation (EC) No 1272/2008 (CLP/GHS)
US Regulation: Listed on TSCA, subject to FIFRA regulation for pesticide formulations
Canada: WHMIS classification available; listed on DSL
Other Regions: Check national biocide regulations for specific concentration limits in products
Worker Protection: Safety data sheets and label instructions are legal requirements at point of use
Restrictions: Safety limits placed on use in some cosmetics, murals, and wood treatment formulations based on toxicity profile and environmental concern
