Product Name: 2-Bromotoluene
Chemical Name: o-Bromotoluene
Synonyms: ortho-Bromotoluene, 1-Bromo-2-methylbenzene
CAS Number: 95-46-5
Molecular Formula: C7H7Br
Manufacturer: Contact supplier or chemical provider
Recommended Uses: Laboratory chemicals, research, industrial synthesis
Emergency Contact Information: Refer to local or national poison centers and chemical safety professionals
GHS Classification: Flammable liquid (Category 3); Acute toxicity – Inhalation, Oral (Category 4); Skin irritation (Category 2); Eye irritation (Category 2A); Specific target organ toxicity
GHS Label Elements: Signal word: Warning; Pictograms: Flame, Exclamation mark
Hazard Statements: Flammable liquid and vapor; Harmful if swallowed or inhaled; Causes skin and eye irritation
Precautionary Statements: Avoid breathing vapors or dust; Keep container tightly closed; Wash hands thoroughly after handling; Wear protective gloves and eye protection
Routes of Exposure: Inhalation, skin absorption, ingestion, eye contact
Most Important Hazards: May cause respiratory tract irritation and organ damage over time
Chemical Name: 2-Bromotoluene
CAS Number: 95-46-5
Concentration: ≥99% pure
Impurities: Trace impurities such as 4-bromotoluene, methyl bromide; levels depend on manufacturer and storage
EC Number: 202-414-9
Inhalation: Move person to fresh air; seek medical attention if symptoms develop; place in recovery position; provide artificial respiration if difficulty breathing occurs
Skin Contact: Remove contaminated clothing; wash thoroughly with soap and water; consult physician for irritation or burns
Eye Contact: Flush with plenty of water for at least 15 minutes; lift eyelids to ensure thorough rinsing; seek medical advice if irritation persists
Ingestion: Rinse mouth with water; do not induce vomiting unless directed by medical personnel; obtain immediate medical attention
Symptoms: Irritation of skin, eyes, respiratory tract; headache, dizziness, drowsiness; gastrointestinal discomfort if ingested
Special Notes to Physicians: Treat symptomatically; no specific antidote known
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray
Unsuitable Media: Direct water jet on burning liquid
Hazards from Combustion: Releases pungent and toxic bromine-containing fumes, carbon oxides
Special Protective Equipment: Firefighters should use self-contained breathing apparatus, full protective gear
Precautions: Evacuate area, do not breathe vapors or fumes
Advice: Contain run-off to prevent environmental contamination; cool containers near fire with water spray
Personal Precautions: Evacuate unnecessary personnel; ventilate area; avoid contact with skin, eyes, clothing
Protective Equipment: Use chemical-resistant gloves, safety goggles, lab coat, and approved respirators
Environmental Precautions: Prevent substance from entering drains, sewers, groundwater; notify relevant authorities in case of large spill
Containment: Absorb with inert material like sand, earth, or vermiculite; do not use combustible materials
Clean-Up Methods: Collect and place in appropriate, labeled waste containers; decontaminate area with soap and water
Handling: Use only in well-ventilated areas; avoid inhalation, ingestion, or contact with skin and eyes; open carefully to avoid splashing
Hygiene: Wash thoroughly after handling; keep food and drink away from working area; remove contaminated clothing before entering eating areas
Storage Conditions: Store in tightly-closed, labeled containers; keep in a cool, dry, well-ventilated place; segregate from oxidizers, acids, foodstuffs
Incompatible Materials: Alkali metals, strong oxidizing agents, strong acids
Packaging Materials: Store in amber glass bottles or containers resistant to brominated organic chemicals
Exposure Limits: No established OSHA, NIOSH, or ACGIH TLVs for this substance; minimize exposure as much as possible
Engineering Controls: Use fume hood or effective local ventilation; install eyewash stations and safety showers in the vicinity
Personal Protection: Wear impervious gloves (nitrile recommended), chemical goggles or face shield, laboratory coat or chemical-resistant apron
Respiratory Protection: Use NIOSH-approved respirator if airborne concentrations become significant or if ventilation inadequate
Environmental Protection: Avoid uncontrolled release; follow established chemical waste disposal procedures
Appearance: Colorless to pale yellow liquid
Odor: Aromatic, mild sweet odor
Melting Point: -24°C
Boiling Point: 183-185°C
Flash Point: 66°C (closed cup)
Flammability: Flammable liquid
Autoignition Temperature: 525°C
Explosion Limits: Data not available
Vapor Pressure: 0.7 mmHg at 25°C
Density: 1.43 g/cm³ at 20°C
Solubility: Insoluble in water; soluble in organic solvents like ethanol, ether, benzene
Viscosity: Not measured
Partition Coefficient (log Kow): 3.5 (estimated)
Molecular Weight: 171.04 g/mol
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Reacts with strong oxidizers, halogens, alkali metals, causing hazardous situations
Hazardous Polymerization: Does not polymerize
Hazardous Decomposition Products: Hydrogen bromide gas, bromine, carbon dioxide, carbon monoxide
Conditions to Avoid: Excessive heat, sparks, open flames, sunlight exposure
Incompatible Materials: Acid chlorides, acid anhydrides, strong bases, strong acids, oxidizing agents
Acute Toxicity: LD50 Oral (rat): 3160 mg/kg; LD50 Dermal (rabbit): data not fully established
Skin Irritation: Causes moderate skin irritation
Eye Irritation: Causes moderate eye irritation, potential for redness, tearing
Inhalation Effects: Headache, nausea, drowsiness, irritation of nose/throat
Chronic Effects: Prolonged or repeated exposure may lead to effects on the central nervous system and liver
Carcinogenicity: No components classified as carcinogenic by IARC, NTP, ACGIH, or OSHA
Mutagenicity: Not classified as mutagenic; limited animal data
Reproductive Toxicity: Insufficient evidence of reproductive impacts; prudent to avoid unnecessary exposure
Other Information: Sensitization not reported; symptoms depend on exposure route and duration
Ecotoxicity: Toxic to aquatic organisms; possible long-term aquatic effects
Persistence and Degradability: Moderately persistent in environment; undergoes slow breakdown by photolysis and biodegradation
Bioaccumulation Potential: High partition coefficient suggests potential for bioaccumulation in aquatic species
Mobility in Soil: Limited water solubility and moderate vapor pressure result in low mobility
Other Adverse Effects: Risk for contamination of soil and groundwater if released uncontrolled; avoid release to environment
Waste Treatment Methods: Dispose of in accordance with federal, state, and local environmental regulations; chemical must be incinerated in a licensed facility
Container Management: Triple-rinse empty containers; puncture or crush and dispose of safely as hazardous chemical waste
Precautions for Disposal: Prevent release into drains or public water supplies; contain and label waste
Disposal of Spill Material: Absorb with inert material, seal in labeled container for proper destruction
Recommended Disposal: High-temperature incineration with flue gas scrubbing to manage hazardous emissions
UN Number: UN 1993
Proper Shipping Name: Flammable liquid, n.o.s. (2-Bromotoluene)
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Labeling Requirement: Flammable liquid
Marine Pollutant: Yes, due to aquatic toxicity
Special Precautions: Secure packaging, segregate from oxidizers and food items, avoid leaks
Regulatory Transport Notes: Comply with DOT, IATA, IMDG, ADR requirements
TSCA Inventory: Listed
REACH Status: Registered in the European Union for specific uses
OSHA Classification: Hazardous chemical as defined by OSHA Hazard Communication Standard
SARA Title III: Not listed as an extremely hazardous substance; routine reporting requirements in case of large spills
California Proposition 65: Not listed as a known carcinogen or reproductive toxicant
WHMIS Classification (Canada): B2 (Flammable Liquid); D2B (Toxic Material Causing Other Toxic Effects)
Other Local Regulations: Restrictions apply depending on jurisdiction; consult environmental health and safety authorities
Label Elements: GHS Pictograms, Hazard Statements, Precautionary Statements required on containers under GHS/OSHA rules
