Product Name: 2-(2-Chloroethoxy)ethanol
Synonyms: Ethanol, 2-(2-chloroethoxy)-; 2-Chloroethyl cellosolve
CAS Number: 622-86-6
Use: Solvent in chemical synthesis, intermediate for pharmaceuticals, laboratory reagent
Manufacturer: Supplier information provided by purchaser
Emergency Contact: Regional poison control center, company emergency hotline
Recommended Restrictions: For industrial and laboratory use only, not for household purposes
Classification: Acute toxicity (oral, dermal), skin and eye irritant, specific organ toxicity after single exposure
GHS Label Elements: Signal word: Warning; Hazard pictograms: Corrosive, exclamation mark
Hazard Statements: Harmful if swallowed or in contact with skin, causes skin and eye irritation, may cause respiratory irritation
Precautionary Statements: Avoid inhalation, wash hands thoroughly after handling, use protective gear for eyes, face, skin, do not eat or drink around chemical
Other Hazards: May release toxic fumes under fire conditions, forms flammable vapors at high temperatures
Chemical Name: 2-(2-Chloroethoxy)ethanol
CAS Number: 622-86-6
Concentration: Pure substance, typically >99%
Impurities: Trace amounts of related glycol ethers, water, possible stabilizers from manufacturing
Molecular Formula: C4H9ClO2
Molecular Weight: 124.57 g/mol
Inhalation: Move affected person outdoors or to fresh air, keep at rest in comfortable position, seek medical attention for symptoms like breathing difficulty or cough
Skin Contact: Remove any contaminated clothing immediately, rinse skin thoroughly with water for at least 15 minutes, obtain medical attention for irritation or burns, launder clothing before reuse
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, get medical assessment as soon as possible
Ingestion: Rinse mouth, do not induce vomiting, never give anything by mouth to an unconscious person, seek urgent medical help and provide product safety data
Most Important Symptoms and Effects: Burning sensation, coughing, headache, abdominal pain, skin redness, eye watering, potential delayed effects on liver and kidneys
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, alcohol-resistant foam
Unsuitable Extinguishing Media: Direct water jet may spread chemical or intensify hazard
Specific Hazards: Formation of toxic and irritating gases including hydrogen chloride, phosgene, carbon monoxide, carbon dioxide
Protective Equipment for Firefighters: Wear full protective suit, positive-pressure self-contained breathing apparatus
Firefighting Instructions: Fight fire from upwind position, keep containers cool by spraying with water, use appropriate protection to avoid inhalation of gases
Personal Precautions: Avoid contact with spilled material, use appropriate personal protective equipment for skin, eyes, and respiratory system
Environmental Precautions: Prevent entry to drains, sewers, basements, or waterways, restrict access to area
Methods for Clean-Up: Absorb small spills using inert material (sand, earth, vermiculite), place in chemical waste containers for disposal, ventilate affected area thoroughly, decontaminate surfaces with water and mild detergent
Handling Cleanup Waste: Prevent accumulation of vapor, wash equipment thoroughly, collect in containers for disposal
Precautions for Safe Handling: Use adequate exhaust ventilation, wear chemical-resistant gloves and goggles, avoid inhaling vapors, prevent skin and eye contact, do not eat or smoke near chemicals
Conditions for Safe Storage: Store in cool, dry, well-ventilated place, keep container tightly closed and away from incompatible substances like strong acids, bases, oxidizers
Special Storage Considerations: Segregate from food and beverages, label all containers clearly, keep out of direct sunlight, use corrosion-resistant shelving
Control Parameters: No official threshold limit value established; consider occupational exposure limits for glycol ethers as guidance
Engineering Controls: Provide local exhaust ventilation to minimize vapor exposure, ensure emergency eyewash stations and showers are accessible
Personal Protective Equipment: Protective clothing including gloves (nitrile, butyl rubber), tightly fitting goggles, face shield for potential splashes, suitable mask or respirator based on airborne concentration
Hygiene Measures: Wash hands, arms, and face after handling, change out of contaminated clothing before eating, drinking, or smoking
Physical State: Liquid
Color: Colorless to pale yellow
Odor: Slight, characteristic
Odor Threshold: Not established
Melting Point/Freezing Point: About -65°C
Boiling Point: 184-186°C
Flash Point: Approximately 83°C (closed cup)
Evaporation Rate: Not rapid under normal conditions, depends on ambient temperature
Flammability: Not classified as flammable, but combustible at elevated temperatures
Explosion Limits: Not readily available, but vapor/air mixtures may be explosive at high temperatures
Vapor Pressure: Very low at room temperature
Vapor Density: Heavier than air
Relative Density: 1.14-1.16 g/cm³
Solubility: Soluble in water, miscible with ethanol, ether
Partition Coefficient (n-octanol/water): Approx 0.3 (estimated)
Autoignition Temperature: >200°C
Decomposition Temperature: No reliable data
Viscosity: Slightly more viscous than water
Chemical Stability: Stable under recommended storage and handling conditions
Possibility of Hazardous Reactions: May react with strong oxidizers, acids, alkali metals, can release chlorinated vapors if heated strongly or with incompatible reagents
Conditions to Avoid: Prolonged contact with air or light, exposure to flames, sparks, sources of intense heat
Incompatible Materials: Strong acids, strong bases, powerful oxidizing agents, alkali metals
Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, carbon dioxide, phosgene in case of combustion or decomposition
Routes of Exposure: Inhalation, skin absorption, ingestion, eye contact
Acute Toxicity: LD50 (oral, rat): 1290 mg/kg; LD50 (dermal, rabbit): about 1500 mg/kg
Skin Irritation: Causes moderate irritation, redness, prolonged contact may cause burns
Eye Irritation: Causes irritation and redness, potential for serious damage upon direct exposure
Respiratory Sensitization: Not confirmed, but vapors may irritate mucous membranes
Chronic Toxicity: Repeated or prolonged exposure may affect liver and kidneys, potential for allergic reactions
Carcinogenicity: Not listed by IARC, NTP, OSHA as a carcinogen
Reproductive Toxicity: No data for reproductive toxicity, but glycol ethers as a class have shown effects in animal studies
Other Health Effects: Headache, dizziness, nausea, drowsiness, possible delayed effects with high exposure
Aquatic Toxicity: Harmful to aquatic organisms in concentrated form
Persistence and Degradability: Readily biodegradable in water and soil, but persistence possible with high volume spills
Bioaccumulative Potential: Low (based on estimated partition coefficient and biodegradability)
Mobility in Soil: High, potentially reaches groundwater with inadequate containment
Other Adverse Effects: Contamination of waterways can disrupt aquatic life, moderate chemical oxygen demand increase
Waste Treatment Methods: Dispose via licensed chemical waste contractor, incinerate in approved facility with flue gas scrubbing
Waste Classification: Hazardous waste, subject to strict local and national regulations
Contaminated Packaging: Rinse containers thoroughly, treat rinse water as hazardous waste, destroy or recycle containers in accordance with regulations
Special Precautions: Do not flush into sewer or open environment, label waste for traceability
UN Number: 2810
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (contains 2-(2-chloroethoxy)ethanol)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Not a marine pollutant, avoid any spillage into waterways
Special Transport Precautions: Ensure containers upright and secure, carry spill preventers, follow regional road and rail transport regulations, include hazard communication in transport documents
OSHA: Not specifically regulated; general duty clause for hazardous chemicals applies
TSCA Inventory: Listed
EU Registration: Subject to REACH regulation requirements
Labeling Requirements: GHS/CLP-compliant hazard designation, pictograms, signal words, risk and safety phrases
SARA 313: Not listed
California Proposition 65: Not currently listed
Other Provisions: Users required to implement workplace risk management, worker training, and environmental protection measures as per local legislation
