Product Name: 1-Chloro-3-Methoxypropane
Synonyms: 3-Methoxypropyl chloride
Chemical Family: Organic chloride compound
Molecular Formula: C4H9ClO
CAS Number: 627-30-5
Recommended Use: Chemical synthesis, laboratory research
Manufacturer/Supplier: Chemical supplier or laboratory supply company
Emergency Phone Number: Refer to supplier or local authority
GHS Classification: Flammable liquid (Category 3), Acute toxicity (oral and inhalation, Category 4), Skin irritant (Category 2), Eye irritant (Category 2A), Specific target organ toxicity – single exposure (Category 3)
Signal Word: Warning
Hazard Statements: Causes skin and serious eye irritation, may cause respiratory irritation, harmful if inhaled or swallowed, flammable liquid and vapor
Pictograms: Exclamation mark, Flame
Precautionary Statements: Avoid breathing vapors, use only in well-ventilated areas, wear protective equipment, keep away from heat, sparks, open flames
Potential Health Effects: Eye contact causes burning and pain, inhalation causes irritation or dizziness, repeated exposure can affect organs
Environmental Hazards: Toxic to aquatic organisms; may cause long-term adverse effects in the environment
Chemical Name: 1-Chloro-3-Methoxypropane
Concentration: >98% (by weight)
Impurities: Trace solvents, water (<2%), no known hazardous stabilizing additives
CAS Number: 627-30-5
Inhalation: Move affected person outdoors to fresh air. Keep comfortable for breathing. Seek medical attention for symptoms like coughing or dizziness.
Skin Contact: Remove contaminated clothing. Wash skin with plenty of soap and water for at least 15 minutes. Get medical attention for persistent irritation.
Eye Contact: Rinse carefully with water for several minutes, holding eyelids open. Remove contact lenses if present and easy to do. Continue rinsing. Seek medical care if discomfort persists.
Ingestion: Do not induce vomiting. Rinse mouth. Seek immediate medical help. Keep at rest.
Advice for Physicians: Symptomatic treatment; no antidote known.
Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam
Unsuitable Media: Water jets may spread the fire
Specific Hazards: Vapors may form explosive mixtures with air, combustion may produce toxic gases such as hydrogen chloride and carbon monoxide
Special Protective Equipment: Firefighters use self-contained breathing apparatus and protective gear
Advice for Firefighters: Stay upwind, move containers away from fire if safe, water spray may be used to cool containers
Personal Precautions: Evacuate unnecessary personnel. Avoid inhalation and contact with skin or eyes. Ventilate area.
Environmental Precautions: Prevent from entering drains, surface or ground water. Notify authorities if spill causes pollution.
Methods for Containment: Contain spill with inert material (sand or vermiculite).
Methods for Cleanup: Collect liquid in containers for disposal. Clean residue with detergent and water. Dispose in accordance with local regulations.
Protective Equipment: Chemical-resistant gloves, goggles, protective clothing, respiratory protection as needed.
Handling: Use only with adequate ventilation. Avoid breathing vapors or mists. No eating, drinking or smoking during use. Wash thoroughly after handling.
Storage Conditions: Keep container tightly closed in a dry, cool and well-ventilated place. Store away from sources of ignition, strong bases and oxidizers.
Incompatible Materials: Strong acids, alkalis and oxidizing agents
Safe Packaging: Use containers approved for flammable materials, clearly labeled
Exposure Limits: No established OSHA or ACGIH exposure limits for this compound
Engineering Controls: Local exhaust ventilation or general dilution ventilation. Use closed system transfer if available.
Personal Protective Equipment:
Appearance: Colorless liquid
Odor: Ether-like, somewhat sweet odor
Odor Threshold: Not established
pH: Not applicable
Melting Point/Freezing Point: -98°C (approximate)
Boiling Point/Range: 120-123°C
Flash Point: 33°C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable liquid and vapor
Explosive Limits: Not determined
Vapor Pressure: 12 mmHg at 20°C
Vapor Density: Heavier than air (approx. 3.1)
Relative Density: 1.021 g/cm³ at 20°C
Solubility: Slightly soluble in water, miscible with organic solvents (alcohol, ether)
Partition coefficient (n-octanol/water): 0.5-1.5 (estimated)
Auto-ignition Temperature: 225°C (estimated)
Decomposition Temperature: Not determined
Viscosity: Not measured
Chemical Stability: Stable under normal storage and handling conditions; avoid prolonged exposure to light and heat
Reactivity: Reacts with strong bases, acids, or oxidizers
Conditions to Avoid: Sources of ignition, excessive heat, static discharge
Hazardous Decomposition Products: Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide
Polymerization: Will not occur under recommended conditions
Acute Toxicity: LD50 (oral, rat): 350 mg/kg (estimated); LD50 (dermal, rabbit): 1800 mg/kg (estimated)
Skin Corrosion/Irritation: Produces moderate redness and dryness
Serious Eye Damage/Irritation: Causes burning, tearing, redness
Respiratory or Skin Sensitization: No reliable data, but similar compounds may cause irritation
Repeated Dose Toxicity: Prolonged exposure may affect liver, kidneys, or central nervous system
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Reproductive Toxicity: No definitive studies, avoid unnecessary exposure
Possible Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Ecotoxicity: Expected to be harmful to aquatic life based on structure-activity relationships
Persistence and Degradability: Not readily biodegradable; may persist in soil and water
Bioaccumulative Potential: Potential for low to moderate bioaccumulation
Mobility in Soil: Moderate mobility; may leach to groundwater in sandy soils
Other Adverse Effects: No specific data for ozone depletion, greenhouse gases, or endocrine disruption
Waste Disposal Methods: Incineration at approved waste facility; do not allow to enter sewers or watercourses
Container Disposal: Empty containers must be triple rinsed and punctured before disposal or return
Regulatory Disposal Requirements: Comply with all local, state, and federal environmental regulations
UN Number: 1993
UN Proper Shipping Name: Flammable Liquid, N.O.S. (contains 1-Chloro-3-Methoxypropane)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Marine Pollutant: Yes, based on structure
Special Precautions for Transport: Keep away from heat sources and direct sunlight; ensure container integrity
Transport Label(s): Flammable Liquid
SARA Title III Section 313: Not specifically listed
TSCA Inventory: Listed
EINECS: 210-991-4
California Proposition 65: Not listed
OSHA Hazard Communication: Meets criteria for hazardous chemicals
WHMIS Classification (Canada): B2 (Flammable liquid), D2B (Toxic material causing other effects)
Other Regulations: Check local, state, and federal requirements for additional information on handling and disposal
