Product Name: 1,2-Benzisothiazolin-3-One
Synonyms: BIT, Benzisothiazolinone
Chemical Formula: C7H5NOS
CAS Number: 2634-33-5
Recommended Use: Preservation of paints, inks, detergents, adhesives, and other industrial fluids
Supplier Details: Full address and emergency contact information required directly from the label or SDS provider
Emergency Phone Number: Local poison control or emergency chemical response line
Classification (GHS): Acute Toxicity (Oral) - Category 4, Skin Corrosion/Irritation - Category 2, Serious Eye Damage/Eye Irritation - Category 1, Skin Sensitization - Category 1
Signal Word: Danger
Hazard Statements: Harmful if swallowed. Causes skin irritation. May cause an allergic skin reaction. Causes serious eye damage.
Precautionary Statements: Avoid contact with skin and eyes. Wear protective clothing, gloves, and face protection. Avoid breathing mist, vapors, or spray. Wash thoroughly after handling.
Pictogram: Exclamation mark, Corrosive
Other: Strong skin and eye irritant; may provoke sensitization after repeated exposure
Chemical Name: 1,2-Benzisothiazolin-3-One
Concentration: 100% (unless diluted for mixture use)
Impurities: May contain trace amounts of related isothiazolinones as unspecified impurities
Other Components: No significant non-hazardous ingredients
Molecular Weight: 151.18 g/mol
Inhalation: Move victim to fresh air. Keep at rest. Provide artificial respiration if breathing is difficult. Seek medical attention.
Ingestion: Rinse mouth with water. Do not induce vomiting. Seek immediate medical help.
Skin Contact: Remove contaminated clothing. Wash thorough ly with soap and water for at least 15 minutes. Seek medical advice for persistent irritation.
Eye Contact: Rinse cautiously with water for at least 15 minutes, lifting eyelids occasionally. Seek medical attention urgently.
Notes for Physicians: Symptomatic treatment. Observe for delayed symptoms such as allergic dermatitis or irritation, and consider possible respiratory sensitization.
Suitable Extinguishing Media: Dry chemical, CO2, water spray, or alcohol-resistant foam
Unsuitable Media: High pressure water jets may cause spread of hazardous contamination
Hazardous Combustion Products: Emits toxic fumes including nitrogen oxides, sulfur oxides, and carbon monoxide during combustion
Protective Equipment: Full protective gear and self-contained breathing apparatus
Fire-Fighting Procedures: Prevent runoff from entering drains and water sources. Use water spray to cool containers exposed to fire. Keep upwind. Avoid breathing smoke.
Personal Precautions: Evacuate unnecessary personnel. Avoid direct contact with substance. Wear suitable chemical-resistant gloves, safety goggles, and protective clothing.
Environmental Precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains or natural watercourses.
Methods for Clean-up: Contain spillage and absorb with inert material such as sand or vermiculite. Scoop into suitable container for disposal. Decontaminate spill area with detergent and water. Ensure ventilation.
Safe Handling: Handling only in well-ventilated areas. Avoid contact with skin, eyes, and clothing. Do not eat, drink, or smoke when using this material. Wash hands thoroughly after handling.
Storage Conditions: Store tightly closed in original container in a cool, dry, well-ventilated place. Protect from direct sunlight, moisture, and heat sources. Keep away from food, drink, and incompatible materials, such as strong oxidizers and reducing agents.
Specific End Uses: Ensure product remains clearly labeled. Restrict access to trained personnel. Observe all regulatory requirements for chemical storage.
Occupational Exposure Limits: No established US OSHA or ACGIH exposure limits for BIT, but minimize workplace exposure to lowest feasible concentration
Engineering Controls: Use local exhaust ventilation to maintain airborne levels below recommended limits. Provide eyewash stations and safety showers in the area of use.
Personal Protective Equipment: Nitrile or neoprene gloves, chemical splash goggles, long sleeves, apron, closed-toe shoes, and suitable respiratory protection for mists or vapors
Hygiene Measures: Remove contaminated clothing immediately. Do not reuse contaminated work clothing. Wash hands, face, and any exposed skin before breaks and at end of work.
Appearance: Off-white to pale yellow crystalline powder or solid
Odor: Mild, characteristic
Odor Threshold: Not available
pH (1% soln): Around 8 (alkaline)
Melting Point: 155-158°C
Boiling Point: Decomposes before boiling
Flash Point: No data, not classified as flammable
Evaporation Rate: Not available
Flammability: Not highly flammable under normal conditions
Vapor Pressure: Negligible at room temperature
Vapor Density: Not applicable
Relative Density: Approximately 1.37 g/cm³
Solubility: Moderately soluble in water, higher solubility in DMF and DMSO
Partition Coefficient (log Kow): ~1.3
Auto-ignition Temperature: Not self-igniting
Decomposition Temperature: Above 150°C may produce hazardous gases
Viscosity: Not applicable (solid)
Chemical Stability: Stable under recommended storage conditions
Conditions to Avoid: Excessive heat, direct sunlight, moisture, contamination with incompatible chemicals
Materials to Avoid: Strong oxidizing agents, strong reducing agents, acids, bases
Hazardous Decomposition Products: Nitrogen oxides, sulfur dioxide, carbon monoxide may form under fire or decomposition
Polymerization: No known hazardous polymerization
Reactivity: Not expected to create new hazardous products at room temperature under normal storage
Acute Toxicity (Oral): LD50 (rat): approximately 400 mg/kg (moderate toxicity)
Inhalation: May cause respiratory irritation, higher exposures can depress central nervous system
Dermal: LD50 (rabbit): above 2000 mg/kg (moderately hazardous)
Skin Corrosion/Irritation: Causes irritation, may provoke strong redness and discomfort
Eye Damage/Irritation: Serious risk of severe, possibly irreversible eye injury
Respiratory Sensitization: Not fully established; repeated exposure may sensitize some individuals
Skin Sensitization: Known to provoke allergic contact dermatitis in exposed workers
Mutagenicity: Animal studies have not shown clear mutagenic potential
Carcinogenicity: Not classified by IARC, NTP, or OSHA as a known carcinogen
Reproductive Toxicity: No conclusive data demonstrating reproductive hazard in animal studies
Other Effects: Chronic overexposure may cause skin irritation, eczema, and rarely systemic effects
Ecotoxicity: Toxic to aquatic organisms, with long-lasting effects. EC50 (Daphnia magna): 1.4 mg/L (48hr). LC50 (fish): ~1.6 mg/L (96hr).
Persistence and Degradability: Biodegradation moderately slow; not considered readily biodegradable
Bioaccumulative Potential: Potential for bioaccumulation considered low, but long-term buildup possible in sediments
Mobility in Soil: Shows moderate mobility, can migrate to groundwater if spilled
Other Adverse Effects: Chronic aquatic hazard due to toxicity and slow degradation
Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations. Transport in tightly sealed containers to licensed chemical waste facility.
Product Disposal: Do not discharge into drains, surface water, or soil. Incinerate or landfill only at approved sites.
Container Disposal: Triple rinse, destroy then dispose of consistent with government regulations. Residues must not contaminate water or food.
Other Information: Always check local authority guidance for chemical and hazardous waste disposal specifics.
UN Number: Not regulated for ground, air, or maritime transport in most jurisdictions when shipped in standard concentrations/formulations
Transport Hazard Class: Not classified as dangerous for transport, but precautions apply for accidental exposure
Packing Group: Not assigned
Environmental Hazards: Potential marine pollutant; avoid uncontrolled releases during loading or unloading
Special Precautions: Avoid spillage, ensure containers remain upright and sealed
Other Transport Requirements: Label according to workplace hazard regulations (not transport class)
US TSCA Inventory: Listed
REACH Status: Registered in the European Union
Workplace Classification: Subject to workplace labeling, PPE, and training requirements under OSHA and similar agencies
SARA Title III: Not subject to SARA reporting requirements
California Proposition 65: Not listed
Other Listings: Referenced in hazard regulations in Canada, EU, Australia, China, and Japan
Inventory Status: Registered or notified in major industrial nations
Labeling: Comply with required hazard communication and safety labeling standards, update as science advances
